Evidence map›Paper›PMID 30855201›Full record

ArticleJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research2019

CCL28 Is Involved in Mucosal IgA Responses, Olfaction, and Resistance to Enteric Infections.

Amanda M Burkhardt, Araceli Perez-Lopez, Irina Ushach, Jovani Catalan-Dibene, Sean-Paul Nuccio, Lawton K Chung, Marcela Hernandez-Ruiz, Christina Carnevale, Manuela Raffatellu, Albert Zlotnik

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Article
  7. Article
  8. International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Amanda M Burkhardt1 Department of Physiology and Biophysics, University of California, Irvine, Irvine, California.
Araceli Perez-Lopez3 Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, California.
Irina Ushach1 Department of Physiology and Biophysics, University of California, Irvine, Irvine, California.
Jovani Catalan-Dibene1 Department of Physiology and Biophysics, University of California, Irvine, Irvine, California.
Sean-Paul Nuccio3 Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, California.
Lawton K Chung3 Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, California.
Marcela Hernandez-Ruiz1 Department of Physiology and Biophysics, University of California, Irvine, Irvine, California.
Christina Carnevale1 Department of Physiology and Biophysics, University of California, Irvine, Irvine, California.
Manuela Raffatellu3 Department of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, California.
Albert Zlotnik1 Department of Physiology and Biophysics, University of California, Irvine, Irvine, California.
University of California, Irvine · USUniversity of California San Diego · USUniversity of San Diego · US

Funding

Nutritional immunity during Salmonella infectionR01AI126277 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAFFATELLU, MANUELA · 2016 to 2020
$1.9M
Characterization of CCL28,CXCL14, and CXCL17, three mucosal chemokinesR01AI093548 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI ZLOTNIK, ALBERT · 2012 to 2016
$1.9M
Development of siderophore-based vaccines against non-typhoidal Salmonella infectionR01AI114625 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NOLAN, ELIZABETH M, RAFFATELLU, MANUELA · 2015 to 2019
$1.9M
Nutritional immunity during Salmonella infectionR37AI126277 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Manuela Raffatellu · 2023 to 2026
$1.8M
The new chemokine CCL28 and its role during Salmonella infectionR21AI121928 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAFFATELLU, MANUELA, ZLOTNIK, ALBERT · 2016 to 2017
$425k
Siderophore-based antibiotics: consequences for the microbiota and bacterial pathogensR21AI126465 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI NOLAN, ELIZABETH M, RAFFATELLU, MANUELA · 2016 to 2017
$404k
Harnessing iron acquisition to hinder enterobacterial pathogenesisR56AI114625 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NOLAN, ELIZABETH M, RAFFATELLU, MANUELA · 2022 to 2022
$400k
NIAID NIH HHS R01 AI093548NIAID NIH HHS R01 AI114625NIAID NIH HHS R01 AI126277NIAID NIH HHS R21 AI121928NIAID NIH HHS R21 AI126465NIAID NIH HHS R37 AI126277NIAID NIH HHS R56 AI114625
6 · The paper itself

Abstract

CCL28 is a mucosal chemokine that has been involved in various responses, including IgA production. We have analyzed its production in human tissues using a comprehensive microarray database. Its highest expression is in the salivary gland, indicating that it is an important component of saliva. It is also expressed in the trachea, bronchus, and in the mammary gland upon onset of lactation. We have also characterized a Ccl28

Indexed as

Adaptive ImmunityAnimalsChemokines, CCGastrointestinal MicrobiomeHomeostasisImmunity, InnateImmunity, MucosalImmunoglobulin AMiceMice, Inbred C57BLMice, KnockoutSalmonella entericaSalmonella Infections, AnimalSmellCcl28 protein, mouseChemokines, CCImmunoglobulin Achemokinesgutinnate immunityvomeronasal organ

Identifiers

PMID30855201
PMCPMC6479244
OpenAlexW2921488449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.