Evidence map›Paper›PMID 30854609›Full record

ReviewCurrent pain and headache reports2019

Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment.

Ivan Urits, Aaron Burshtein, Medha Sharma, Lauren Testa, Peter A Gold, Vwaire Orhurhu, Omar Viswanath, Mark R Jones, Moises A Sidransky, Boris Spektor and 1 more

6 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 271 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
271citing papers in PubMed, 14 pooled it
36.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05111782 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Age Bias on Biopsychosocial Factors in Persons With Non-specific Low Back Pain.

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2025Enrolled280ConditionsLow Back PainArmsSymptom Modulation Approach, Movement Control Approach, Functional Optimization Approach
NCT05272098 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparative Effects of Myofascial Release Therapy and Endurance Training of Trunk Extensor Muscles on Pain, Disability and Muscle Endurance in Patients With Mechanical Back Pain.

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2022Enrolled24ConditionsBack Pain, LowArmsGroup A will receive myofascial release therapy + conventional physical therapy, Group B will receive endurance training of the trunk extensor muscles + conventional physical therapy
NCT05402631 unknown statusnot on this mapstarted 2022, after this paper: background citation

Can Patient Expectations Influence Pain Reduction After Epidural Injections in Patients With Low Back Pain? An Observational Cohort Study

TypeobservationalSponsorOspedale Regionale di LuganoRan2022 to 2022Enrolled80ConditionsExpectations, Back Pain, Back Pain Lower Back Chronic, Satisfaction, PatientArmsEpidural Injection, Periradicular Injection
NCT05877469 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Mat Pilates Versus Functional Training on Pain, Range of Motion and Disability in Mechanical Low Back Pain

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled44ConditionsMechanical Low Back PainArmsMat pilates Training, Functional Training
NCT06360341 nacompletednot on this mapstarted 2024, after this paper: background citation

Feasibility and Acceptability of an Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorUniversity of FloridaRan2024 to 2024Enrolled30ConditionsLow Back Pain, Mechanical, Acute PainArmsEmergency Department Digital Pain Self-Management Intervention (EDPSI), Routine Discharge Care
NCT07768033 nacompletednot on this mapstarted 2026, after this paper: background citation

The effect of chair-assisted yoga practice on sleep quality and pain levels in elderly individuals living in nursing homes

TypeinterventionalSponsorRüveyda BerkRan2026 to 2026Enrolled36ConditionsSleep Quality, PainArmsChair-Supported Yoga
3 · Its place in the literature

Who cites it

271 citing papers in PubMed, 14 syntheses or guidelines pooled it, 605 citations in OpenAlex.

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  3. Management of sacroiliac joint pain: current concepts.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
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  5. Overview of Available Treatments and Their Limitations for Hypertrophic Facet Joints-A Systematic Review of the Literature.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
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  20. Early functional training is not superior to routine rehabilitation in improving walking distance and multifidus atrophy after lumbar fusion: a randomized controlled trial with 6-month follow-up.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Trial

211 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Ivan UritsDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA. iurits@bidmc.harvard.edu.
Aaron BurshteinDepartment of Orthopedic Surgery, Hofstra-Northwell Health System, Great Neck, NY, 11021, USA.
Medha SharmaDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Lauren TestaDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Peter A GoldDepartment of Orthopedic Surgery, Hofstra-Northwell Health System, Great Neck, NY, 11021, USA.
Vwaire OrhurhuDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Omar ViswanathValley Anesthesiology and Pain Consultants, Phoenix, AZ, USA.
Mark R JonesDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Moises A SidranskyDepartment of Anesthesiology, University of Arizona College of Medicine-Phoenix, Tyler, TX, USA.
Boris SpektorDepartment of Anesthesiology, Emory School of Medicine, Atlanta, GA, 30308, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Science Center, New Orleans, LA, 70112, USA.
Harvard University · USNorthwell Health · USBeth Israel Deaconess Medical Center · USCreighton University · USEmory University · USLouisiana State University Health Sciences Center New Orleans · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewLow back pain encompasses three distinct sources: axial lumbosacral, radicular, and referred pain. Annually, the prevalence of low back pain in the general US adult population is 10-30%, and the lifetime prevalence of US adults is as high as 65-80%. RECENT

findingsPatient history, physical exam, and diagnostic testing are important components to accurate diagnosis and identification of patient pathophysiology. Etiologies of low back pain include myofascial pain, facet joint pain, sacroiliac joint pain, discogenic pain, spinal stenosis, and failed back surgery. In chronic back pain patients, a multidisciplinary, logical approach to treatment is most effective and can include multimodal medical, psychological, physical, and interventional approaches. Low back pain is a difficult condition to effectively treat and continues to affect millions of Americans every year. In the current investigation, we present a comprehensive review of low back pain and discuss associated pathophysiology, diagnosis, and treatment.

Indexed as

HumansLow Back PainAxial low back painLow back painLumbosacral painRadiculopathyReferred low back pain

Identifiers

PMID30854609
OpenAlexW2920922304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.