Evidence map›Paper›PMID 30854444›Full record

ArticleTomography (Ann Arbor, Mich.)2019

Habitats in DCE-MRI to Predict Clinically Significant Prostate Cancers.

Nestor Andres Parra, Hong Lu, Jung Choi, Kenneth Gage, Julio Pow-Sang, Robert J Gillies, Yoganand Balagurunathan

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Predictions of Oncotype DXBioengineering (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. The value of habitat analysis based onBMC medical imaging · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Radiomics Improves Cancer Screening and Early Detection.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nestor Andres ParraDepartments of Cancer Physiology.
Hong LuDepartments of Cancer Physiology.
Jung ChoiRadiology, and.
Kenneth GageRadiology, and.
Julio Pow-SangUrology, H.L. Moffitt Cancer Center, Tampa, FL; and.
Robert J GilliesDepartments of Cancer Physiology.
Yoganand BalagurunathanDepartments of Cancer Physiology.

Funding

"Research Supplement to Promote Diversity in Health-Related Research", as part of Moffitt PS-OC, "Cancer as a Complex adaptive System"U54CA193489 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ANDERSON, ALEXANDER ROBERTSON ALLAN, GATENBY, ROBERT A · 2015 to 2020
$12.5M
MRI Imaging and Genetic Signatures to Manage Prostate Cancer OverdiagnosisR01CA189295 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI POLLACK, ALAN · 2014 to 2018
$3.2M
(PQC4) Habitats in Prostate CancerR01CA190105 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI BALAGURUNATHAN, YOGANAND, GILLIES, ROBERT J. · 2014 to 2017
$2.8M
NCI NIH HHS R01 CA189295NCI NIH HHS R01 CA190105NCI NIH HHS U54 CA193489
6 · The paper itself

Abstract

Prostate cancer identification and assessment of clinical significance continues to be a challenge. Routine multiparametric magnetic resonance imaging has shown to be useful in assessing disease progression. Although dynamic contrast-enhanced imaging (DCE) has the ability to characterize perfusion across time and has shown enormous utility, radiological assessment (Prostate Imaging-Reporting and Data System or PIRADS version 2) has limited its use owing to lack of consistency and nonquantitative nature. In our work, we propose a systematic methodology to quantify perfusion dynamics for the DCE imaging. Using these metrics, 7 different subregions or

Indexed as

Contrast MediaDiffusion Magnetic Resonance ImagingHumansImage-Guided BiopsyImage Interpretation, Computer-AssistedMachine LearningMalePredictive Value of TestsProstatic NeoplasmsRetrospective StudiesSensitivity and SpecificityContrast MediaDCEhabitatsmachine learningMRIprostate cancerradiomics

Identifiers

PMID30854444
PMCPMC6403034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.