Evidence map›Paper›PMID 30854440›Full record

ArticleTomography (Ann Arbor, Mich.)2019

Multicenter Repeatability Study of a Novel Quantitative Diffusion Kurtosis Imaging Phantom.

Dariya I Malyarenko, Scott D Swanson, Amaresha S Konar, Eve LoCastro, Ramesh Paudyal, Michael Z Liu, Sachin R Jambawalikar, Lawrence H Schwartz, Amita Shukla-Dave, Thomas L Chenevert

Open access · goldAbstract readEvaluation StudyMulticenter Study
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dariya I MalyarenkoDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI.
Scott D SwansonDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI.
Amaresha S KonarDepartments of Medical Physics and.
Eve LoCastroDepartments of Medical Physics and.
Ramesh PaudyalDepartments of Medical Physics and.
Michael Z LiuDepartment of Radiology, Columbia University Irving Medical Center, New York, NY.
Sachin R JambawalikarDepartment of Radiology, Columbia University Irving Medical Center, New York, NY.
Lawrence H SchwartzDepartment of Radiology, Columbia University Irving Medical Center, New York, NY.
Amita Shukla-DaveDepartments of Medical Physics and.
Thomas L ChenevertDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI.
Memorial Sloan Kettering Cancer Center · USColumbia University Irving Medical Center · USUniversity of Michigan–Ann Arbor · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
QUANTITATION OF HUMAN BRAIN TUMOR THERAPY RESPONSE BY MRP01CA085878 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHENEVERT, THOMAS L · 2001 to 2017
$31.9M
Quantitative DW-MRI for Early Breast Cancer Treatment Response AssessmentU01CA166104 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHENEVERT, THOMAS L, GALBAN, CRAIG J · 2012 to 2019
$4.1M
Quantitative imaging tools to derive DW-MRI oncological biomarkersU01CA211205 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DAVE, AMITA, SCHWARTZ, LAWRENCE H · 2017 to 2021
$3.4M
NCI NIH HHS P01 CA085878NCI NIH HHS P30 CA008748NCI NIH HHS U01 CA166104NCI NIH HHS U01 CA211205
6 · The paper itself

Abstract

Quantitative kurtosis phantoms are sought by multicenter clinical trials to establish accuracy and precision of quantitative imaging biomarkers on the basis of diffusion kurtosis imaging (DKI) parameters. We designed and evaluated precision, reproducibility, and long-term stability of a novel isotropic (i)DKI phantom fabricated using four families of chemicals based on vesicular and lamellar mesophases of liquid crystal materials. The constructed iDKI phantoms included negative control monoexponential diffusion materials to independently characterize noise and model-induced bias in quantitative kurtosis parameters. Ten test-retest DKI studies were performed on four scanners at three imaging centers over a six-month period. The tested prototype phantoms exhibited physiologically relevant apparent diffusion, D

Indexed as

Diffusion Magnetic Resonance ImagingEquipment DesignHumansImage Interpretation, Computer-AssistedLiquid CrystalsPhantoms, ImagingReproducibility of ResultsTemperaturediffusion kurtosismicro-scale lamellar vesiclesrepeatabilitytemporal stabilitytunable parameters

Identifiers

PMID30854440
PMCPMC6403043
OpenAlexW2940326735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.