Evidence map›Paper›PMID 30854439›Full record

Trial reportTomography (Ann Arbor, Mich.)2019

Quantitative Non-Gaussian Intravoxel Incoherent Motion Diffusion-Weighted Imaging Metrics and Surgical Pathology for Stratifying Tumor Aggressiveness in Papillary Thyroid Carcinomas.

David Aramburu Núñez, Yonggang Lu, Ramesh Paudyal, Vaios Hatzoglou, Andre L Moreira, Jung Hun Oh, Hilda E Stambuk, Yousef Mazaheri, Mithat Gonen, Ronald A Ghossein and 3 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Tomography (Ann Arbor, Mich.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A comparative study of methods for determining Intravoxel incoherent motion parameters in cervix cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

David Aramburu NúñezDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Yonggang LuDepartment of Radiology, Medical College of Wisconsin, Milwaukee, WI.
Ramesh PaudyalDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Vaios HatzoglouDepartments of Radiology.
Andre L MoreiraDepartment of Pathology, NYU Langone Medical Center, New York, NY.
Jung Hun OhDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Hilda E StambukDepartments of Radiology.
Yousef MazaheriDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Mithat GonenEpidemiology and Biostatistics.
Ronald A GhosseinPathology.
Ashok R ShahaSurgery, and.
R Michael TuttleMedicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Amita Shukla-DaveDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Memorial Sloan Kettering Cancer Center · USMedical College of Wisconsin · USNYU Langone Health · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
SPORE in Thyroid CancerP50CA172012 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI FAGIN, JAMES A · 2014 to 2018
$10.3M
Quantitative imaging tools to derive DW-MRI oncological biomarkersU01CA211205 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DAVE, AMITA, SCHWARTZ, LAWRENCE H · 2017 to 2021
$3.4M
Predictive MRI metrics for tumor aggressiveness in micropapillary thyroid cancerR21CA176660 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DAVE, AMITA · 2014 to 2015
$737k
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA172012NCI NIH HHS R21 CA176660NCI NIH HHS U01 CA211205
6 · The paper itself

Abstract

We assessed a priori aggressive features using quantitative diffusion-weighted imaging metrics to preclude an active surveillance management approach in patients with papillary thyroid cancer (PTC) with tumor size 1-2 cm. This prospective study enrolled 24 patients with PTC who underwent pretreatment multi-b-value diffusion-weighted imaging on a GE 3 T magnetic resonance imaging scanner. The apparent diffusion coefficient (ADC) metric was calculated from monoexponential model, and the perfusion fraction (

Indexed as

AdultAgedDiffusion Magnetic Resonance ImagingFemaleHumansImage Interpretation, Computer-AssistedMaleMiddle AgedProspective StudiesROC CurveSensitivity and SpecificityThyroid Cancer, PapillaryThyroid NeoplasmsUltrasonographyWatchful Waitingdiffusion-weighted imagingGaussian and non-Gaussianmulti b-valuepapillary thyroid carcinomatumor aggressiveness

Identifiers

PMID30854439
PMCPMC6403039
OpenAlexW2942599508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.