Evidence map›Paper›PMID 30854307›Full record

ArticleAnnals of cardiothoracic surgery2019

Outcomes of venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock: systematic review and meta-analysis.

Ashley R Wilson-Smith, Yulia Bogdanova, Stephanie Roydhouse, Kevin Phan, David H Tian, Tristan D Yan, Antonio Loforte

Abstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Extracorporeal membrane oxygenation for critically ill adults.The Cochrane database of systematic reviews · 2023
    Pooled it
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  14. Extracorporeal Membrane Oxygenation.Deutsches Arzteblatt international · 2022
    Review
  15. Mechanical circulatory support in acute myocardial infarction and cardiogenic shock: Challenges and importance of randomized control trials.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashley R Wilson-SmithThe Collaborative Research Group (CORE), Macquarie University, Sydney, Australia.
Yulia BogdanovaThe University of New South Wales, Faculty of Medicine, Sydney, Australia.
Stephanie RoydhouseThe University of New South Wales, Faculty of Medicine, Sydney, Australia.
Kevin PhanThe Collaborative Research Group (CORE), Macquarie University, Sydney, Australia.
David H TianThe Collaborative Research Group (CORE), Macquarie University, Sydney, Australia.
Tristan D YanThe Collaborative Research Group (CORE), Macquarie University, Sydney, Australia.
Antonio LoforteDepartment of Cardiovascular Surgery and Transplantation, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite advances in management techniques and medical therapy, refractory cardiogenic shock remains a life-threatening condition with high mortality rates. The present systematic review and meta-analysis aims to explore the outcomes associated with venoarterial extracorporeal membrane oxygenation (VA-ECMO) use in the setting of refractory cardiogenic shock, stratified per survivorship.

methodsA literature search was performed using three electronic databases from the date of their inception up to June 2018. The literature search and subsequent data extraction were performed by two independent reviewers. Digitized survival data were extracted from Kaplan-Meier curves in order to re-create the original patient data using an iterative algorithm and were subsequently aggregated for analysis.

resultsFifty-two studies were included, with 44 undergoing quantitative analysis. A total of 17,515 patients were identified, with a mean age of 58.4±9.4 years and a mean duration of ECMO support of 5.1±2.6 days; 68.7% of the patients were male. Aggregated survival rates at 1, 2, 3 and 5 years were 36.7%, 34.8%, 33.8% and 29.9%, respectively.

conclusionsThe present systematic review illustrates the expected survival results for VA-ECMO in the intermediate- to long-term. Extended follow-up and standardized reporting measures are urgently needed in order to carry out more definitive subgroup analyses.

Indexed as

ECLSExtracorporeal membrane oxygenation (ECMO)refractory cardiogenic shock

Identifiers

PMID30854307
PMCPMC6379189

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.