ArticleSAGE open medical case reports2019
Fournier's gangrene as an initial manifestation of acute promyelocytic leukemia: A case report and review of the literature.
Article in SAGE open medical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Management of Fournier's gangrene during the Covid-19 pandemic era: make a virtue out of necessity.Basic and clinical andrology · 2022Article
- Fournier's Gangrene in Patients with Oncohematological Diseases: A Systematic Review of Published Cases.Healthcare (Basel, Switzerland) · 2021Review
- The skin and soft tissue infections in hematological patients.Current opinion in infectious diseases · 2020Review
- Fournier Gangrene in the Emergency Department: Diagnostic Dilemmas, Treatments and Current Perspectives.Open access emergency medicine : OAEM · 2020Review
- Fournier's Gangrene and Intravenous Drug Abuse: an Unusual Case Report and Review of The Literature.Open medicine (Warsaw, Poland) · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fournier's gangrene is classically associated with diabetes mellitus and alcohol use disorder. While it is associated with chemotherapy, there are few case reports of Fournier's gangrene as the initial presentation of acute myelogenous leukemia. A 38-year-old male presented with progressive scrotal swelling and hematochezia. Blood cell count showed depression of all cell lines without myeloblasts. He received broad-spectrum antibiotics and underwent surgical debridement once. Urgent bone marrow biopsy confirmed acute promyelocytic leukemia. The patient was started on chemotherapy. He was discharged without relapse of the infection. This is the fourth case of acute myelogenous leukemia presenting as Fournier's gangrene in the literature and the only case to have survived. This brings forth a possible diagnostic consideration in patients without obvious predisposing risk factors for Fournier's gangrene, particularly in those with pancytopenia. Coordination with surgical services as well as hematology/oncology specialists is imperative to survival of these dual diagnosis patients.
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