Evidence map›Paper›PMID 30854014›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Safflower Yellow B Protects Brain against Cerebral Ischemia Reperfusion Injury through AMPK/NF-kB Pathway.

Shibin Du, Youliang Deng, Hongjie Yuan, Yanyan Sun

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
9.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Frontiers in pharmacology · 2025
    Review
  3. Review
  4. Anatomy & cell biology · 2024
    Article
  5. Review
  6. Neuroprotective effect ofFrontiers in pharmacology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Pharmacological Activities of Safflower Yellow and Its Clinical Applications.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  11. Review
  12. Article
  13. Safflower yellow pigment and SanqiAnnals of translational medicine · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shibin Du *Department of Anesthesiology, Shenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen University, Shenzhen 518055, China.ORCID 0000-0002-2113-2438
Youliang Deng *Department of Anesthesiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Hongjie YuanDepartment of Pain Medicine, Nantong Hospital of Traditional Chinese Medicine, Nantong 226001, China.
Yanyan SunDepartment of Anesthesiology, Shenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen University, Shenzhen 518055, China.ORCID 0000-0002-6735-5725
Shenzhen University · CNAnyang Hospital of Traditional Chinese Medicine · CNArmy Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation had showed its important role in the pathogenesis of cerebral ischemia and secondary damage. Safflower yellow B (SYB) had neuroprotective effects against oxidative stress-induced brain injuries, but the mechanisms were still largely unknown to us. In this study, we tried to investigate the anti-inflammation effects of SYB and the possible roles of AMPK/NF-

Identifiers

PMID30854014
PMCPMC6378026
OpenAlexW2912267443

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.