Evidence map›Paper›PMID 30853987›Full record

ArticleInternational journal of analytical chemistry2019

Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma.

Žane Temova Rakuša, Robert Roškar, Anita Klančar Andrejc, Tina Trdan Lušin, Nataša Faganeli, Iztok Grabnar, Aleš Mrhar, Albin Kristl, Jurij Trontelj

Open access · goldAbstract read
In one paragraph

Article in International journal of analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Žane Temova RakušaUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Robert RoškarUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Anita Klančar AndrejcUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Tina Trdan LušinUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Nataša FaganeliUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Iztok GrabnarUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Aleš MrharUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.ORCID 0000-0002-3186-0826
Albin KristlUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Jurij TronteljUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.ORCID 0000-0002-2558-1425
University of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple, fast, and cost-effective LC-MS/MS method for quantification of rifampicin in human plasma was developed and fully validated. The plasma samples containing rifampicin and isotopically labelled internal standard rifampicin D8, were cleaned up using a Captiva ND Lipids filtration plate. Chromatographic separation was achieved on an 1290 Infinity liquid chromatograph coupled to 6460 Triple Quadrupole operated in positive mode on a core-shell Kinetex C18 column (50 × 2.1 mm, 2.6

Identifiers

PMID30853987
PMCPMC6377990
OpenAlexW2911552688

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.