Evidence map›Paper›PMID 30853932›Full record

ArticleFrontiers in neurology2019

Amide Proton Transfer MRI Signal as a Surrogate Biomarker of Ischemic Stroke Recovery in Patients With Supportive Treatment.

Lu Yu, Yuhui Chen, Min Chen, Xiaojie Luo, Shanshan Jiang, Yi Zhang, Haibo Chen, Tao Gong, Jinyuan Zhou, Chunmei Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Amide proton transfer MRI may reflect effective reperfusion and predict functional outcomes in patients with ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Lu YuDepartment of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Yuhui ChenDepartment of Neurology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Min ChenDepartment of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Xiaojie LuoDepartment of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Shanshan JiangDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Yi ZhangKey Laboratory for Biomedical Engineering of Ministry of Education, Center for Brain Imaging Science and Technology, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China.
Haibo ChenDepartment of Neurology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Tao GongDepartment of Neurology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Jinyuan ZhouDivision of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.
Chunmei LiDepartment of Radiology, Beijing Hospital, National Center of Gerontology, Beijing, China.
Beijing Hospital · CNJohns Hopkins University · USZhejiang University · CN

Funding

Amide Proton Transfer (APT) MRI of Brain Tumors at 3T and 7TR01EB009731 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2009 to 2016
$2.9M
Academic-Industrial Partnership to Develop Clinical Brain Cancer ImagingR01CA166171 · NCI · JOHNS HOPKINS UNIVERSITY · PI VAN ZIJL, PETER CM, ZHOU, JINYUAN · 2013 to 2017
$2.4M
Amide Proton Transfer (APT) MRI of Brain Tumors at 3TR01CA228188 · NCI · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2019 to 2022
$1.6M
Development of Novel Functional Markers for TBI Using Molecular MRIUG3NS106937 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KOEHLER, RAYMOND CHARLES, ZHOU, JINYUAN · 2018 to 2019
$859k
Mast Cell Stabilization and Neonatal Encephalopathy: Preclinical studies in the IR21NS083425 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI VANNUCCI, SUSAN J · 2013 to 2014
$463k
NCI NIH HHS R01 CA166171NCI NIH HHS R01 CA228188NIBIB NIH HHS R01 EB009731NINDS NIH HHS R21 NS083425NINDS NIH HHS UG3 NS106937
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acidosisAPTinfarctionischemiamagnetic resonance imagingstroke

Identifiers

PMID30853932
PMCPMC6395437
OpenAlexW2915495498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.