Evidence map›Paper›PMID 30853878›Full record

ArticleAdvanced functional materials2017

Nanotechnology for Neuroscience: Promising Approaches for Diagnostics, Therapeutics and Brain Activity Mapping.

Anil Kumar, Aaron Tan, Joanna Wong, Jonathan Clayton Spagnoli, James Lam, Brianna Diane Blevins, Natasha G, Lewis Thorne, Keyoumars Ashkan, Jin Xie and 1 more

Abstract read
In one paragraph

Article in Advanced functional materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anil KumarState Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China.
Aaron TanUCL Medical School, University College London (UCL), London, United Kingdom.
Joanna WongImperial College School of Medicine, Imperial College London,London, United Kingdom.
Jonathan Clayton SpagnoliDepartment of Chemistry, Bio-Imaging Research Center, University of Georgia, Athens, Georgia 30602, United States.
James LamUCL Medical School, University College London (UCL), London, United Kingdom.
Brianna Diane BlevinsDepartment of Chemistry, Bio-Imaging Research Center, University of Georgia, Athens, Georgia 30602, United States.
Natasha GUCL Medical School, University College London (UCL), London, United Kingdom.
Lewis ThorneDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
Keyoumars AshkanDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, King's College London, London, United Kingdom.
Jin XieDepartment of Chemistry, Bio-Imaging Research Center, University of Georgia, Athens, Georgia 30602, United States.
Hong LiuState Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China.

Funding

Nanoscintillator-based X-ray sensitizers to enable efficient NSCLC treatment with X-ray irradiationR01EB022596 · NIBIB · UNIVERSITY OF GEORGIA · PI XIE, JIN · 2017 to 2020
$1.9M
NIBIB NIH HHS R01 EB022596
6 · The paper itself

Abstract

Unlocking the secrets of the brain is a task fraught with complexity and challenge - not least due to the intricacy of the circuits involved. With advancements in the scale and precision of scientific technologies, we are increasingly equipped to explore how these components interact to produce a vast range of outputs that constitute function and disease. Here, an insight is offered into key areas in which the marriage of neuroscience and nanotechnology has revolutionized the industry. The evolution of ever more sophisticated nanomaterials culminates in network-operant functionalized agents. In turn, these materials contribute to novel diagnostic and therapeutic strategies, including drug delivery, neuroprotection, neural regeneration, neuroimaging and neurosurgery. Further, the entrance of nanotechnology into future research arenas including optogenetics, molecular/ion sensing and monitoring, and piezoelectric effects is discussed. Finally, considerations in nanoneurotoxicity, the main barrier to clinical translation, are reviewed, and direction for future perspectives is provided.

Indexed as

brain activity mapping (BAM)nanoneurosciencenanoneurotoxicityneural regenerationneuroimagingoptogenetics

Identifiers

PMID30853878
PMCPMC6404766

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.