Evidence map›Paper›PMID 30853830›Full record

ArticleJournal of pediatric infectious diseases2019

Biofilm biology and vaccine strategies for otitis media due to nontypeable

Laura A Novotny, Kenneth L Brockman, Elaine M Mokrzan, Joseph A Jurcisek, Lauren O Bakaletz

Open access · greenAbstract read
In one paragraph

Article in Journal of pediatric infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
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  4. European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  5. Exploiting haem-iron dependence of nontypeableFrontiers in cellular and infection microbiology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Panel 3: Genomics, precision medicine and targeted therapies.International journal of pediatric otorhinolaryngology · 2020
    Review
  16. Panel 8: Vaccines and immunology.International journal of pediatric otorhinolaryngology · 2020
    Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura A NovotnyCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
Kenneth L BrockmanCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
Elaine M MokrzanCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
Joseph A JurcisekCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
Lauren O BakaletzCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, OH, USA.
The Ohio State University · USNationwide Children's Hospital · US

Funding

DETERMINANTS OF H. INFLUENZAE VIRULENCE IN OTITIS MEDIAR01DC003915 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI GOODMAN, STEVEN D · 1999 to 2025
$12.5M
Novel immunotherapeutics for the management of otitis media due to H. influenzaeR01DC011818 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAKALETZ, LAUREN O, GOODMAN, STEVEN D · 2011 to 2020
$5.4M
Otitis media: role of epigenetic regulation on NTHI pathogenesis and optimal vaccine designR01DC015688 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAKALETZ, LAUREN O, JENNINGS, MICHAEL PAUL · 2016 to 2020
$2.2M
NIDCD NIH HHS R01 DC003915NIDCD NIH HHS R01 DC011818NIDCD NIH HHS R01 DC015688
6 · The paper itself

Abstract

Otitis media (OM) is one of the most common diseases of childhood, and nontypeable

Indexed as

DNABII proteinseDNAEPSintegration host factorphasevarionPilAType IV pilus

Identifiers

PMID30853830
PMCPMC6402341
OpenAlexW2864918741

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.