Evidence map›Paper›PMID 30853715›Full record

ArticleIEEE journal of solid-state circuits2017

A Fully Integrated CMOS Fluorescence Biochip for DNA and RNA Testing.

Arun Manickam, Rituraj Singh, Mark McDermott, Nicholas Wood, Sara Bolouki, Pejman Naraghi-Arani, Kirsten Johnson, Robert G Kuimelis, Gary Schoolnik, Arjang Hassibi

Open access · greenAbstract read
In one paragraph

Article in IEEE journal of solid-state circuits, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. An RFID-Inspired One-Step Packaged Multimode Bio-Analyzer with Vacuum Microfluidics for Point-of-Care Diagnostics.Digest of technical papers. IEEE International Solid-State Circuits Conference · 2025
    Article
  5. Review
  6. Review
  7. Surface-modified CMOS biosensors.Frontiers in bioengineering and biotechnology · 2024
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Arun ManickamInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Rituraj SinghInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Mark McDermottInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Nicholas WoodInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Sara BoloukiInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Pejman Naraghi-AraniInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Kirsten JohnsonInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Robert G KuimelisInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Gary SchoolnikInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Arjang HassibiInSilixa, Inc., 1000 Hamlin Ct., Sunnyvale, CA 94089, United States.
Insilixa (United States) · US

Funding

CMOS-Integrated Fluorescence Biochip SBIR Phase II Grant ApplicationR44HG007626 · NHGRI · INSILIXA, INC. · PI HASSIBI, ARJANG · 2015 to 2016
$1.5M
NHGRI NIH HHS R44 HG007626
6 · The paper itself

Abstract

Design and successful implementation of a fully-integrated CMOS fluorescence biochip for DNA/RNA testing in molecular diagnostics (MDx) is presented. The biochip includes a 32×32 array of continuous wave fluorescence detection biosensing elements. Each biosensing element is capable of having unique DNA probe sequences, wavelength-selective multi-dielectric emission filter (OD of 3.6), resistive heater for thermal cycling, and a high performance and programmable photodetector. The dimension of each biosensor is 100

Indexed as

BiochipBiosensorFluorescence SpectroscopyImage SensorsInfectious DiseaseMicroarrayMolecular DiagnosticsNucleic AcidOptical FilterPolymerase Chain Reaction

Identifiers

PMID30853715
PMCPMC6407865
OpenAlexW2766485669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.