Evidence map›Paper›PMID 30853460›Full record

ReviewClinica chimica acta; international journal of clinical chemistry2019

Point of care testing for infectious diseases.

Hui Chen, Kengku Liu, Zhao Li, Ping Wang

Open access · greenAbstract readReview
In one paragraph

Review in Clinica chimica acta; international journal of clinical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 265 citations in OpenAlex.

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  18. Mass of components and material distribution in lateral flow assay kits.Bulletin of the World Health Organization · 2025
    Article
  19. Article
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hui ChenDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Kengku LiuDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Zhao LiDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Ping WangDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address: Ping.Wang2@uphs.upenn.edu.
University of Pennsylvania · US

Funding

Development of a Point-of-Care Volumetric Bar-Chart Chip for Drug QuantitationR01DA035868 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI QIN, LIDONG, WANG, PING · 2013 to 2020
$4.3M
NIDA NIH HHS R01 DA035868
6 · The paper itself

Abstract

Infectious diseases are caused by pathogenic microorganisms and can be transmitted between individuals and populations thus threatening the general public health and potentially the economy. Efficient diagnostic tools are needed to provide accurate and timely guidance for case identification, transmission disruption and appropriate treatment administration. Point of care (POC) tests provide actionable results near the patient and thereby serve as a personal "radar". In this review, we review clinical needs for POC testing for several major pathogens, including malaria parasites, human immunodeficiency virus (HIV), human papillomavirus (HPV), dengue, Ebola and Zika viruses and Mycobacterium tuberculosis (TB). We compare different molecular approaches, including pathogen nucleic acid and protein, circulating microRNA and antibodies, used in the POC tests. Finally, we review recent advances in novel POC technologies focusing on microfluidic and plasmonic-based approaches.

Indexed as

Point-of-Care TestingBiomarkersCommunicable DiseasesHumansBiomarkers

Identifiers

PMID30853460
PMCPMC6462423
OpenAlexW2921430890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.