ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2019
Serum amyloid A and plasma protein electrophoresis fractions in farmed white-tailed deer.
Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Serum Concentrations of Imidazole Dipeptides and Serum Amyloid A in a Bottlenose Dolphin (Animals : an open access journal from MDPI · 2025Article
- Establishing serum protein electrophoresis reference intervals in free-ranging barren-ground caribou (Frontiers in veterinary science · 2025Article
- Article
- Diagnostic value of serum amyloid A in differentiating the inflammatory disorders in wild birds.Frontiers in veterinary science · 2024Article
- Blood analytes of clinically normal and diseased neonatal and weaned farmed white-tailed deer (The veterinary quarterly · 2023Article
- Estimating parasite-condition relationships and potential health effects for fallow deer (International journal for parasitology. Parasites and wildlife · 2023Article
- Protein Electrophoresis and Haptoglobin Values for Captive Bongo (Frontiers in veterinary science · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tools to measure the acute-phase response have been utilized widely in veterinary medicine. Evaluation by plasma protein electrophoresis (PPEP) has become an increasingly common assay in veterinary clinical pathology. Commercial reagents for serum amyloid A (SAA) have been validated for use in a variety of wildlife species. We analyzed samples from 29 healthy fawns and 60 healthy adult farmed white-tailed deer (WTD; Odocoileus virginianus) using an automated assay for SAA and a semi-automated method for PPEP. The robust statistical method for reference interval generation was used. SAA levels in fawns (0.1-26 mg/L) were found to be significantly higher than those in adults (0.1-5 mg/L, p < 0.01). The mean total protein was significantly lower in fawns (48 ± 10 g/L, p < 0.01) than in adults (73 ±5 g/L). The albumin-to-globulin ratio was also lower in fawns (0.56 ± 0.14) than in adults (1.25 ± 0.19, p < 0.01). Changes in SAA levels were observed in a variety of clinically abnormal animals. The combined use of the automated and semi-automated assays in our study may provide an additional valuable assessment tool in the care of captive WTD populations, for research studies, and for monitoring free-ranging animals.
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