Evidence map›Paper›PMID 30852785›Full record

ArticleJournal of autism and developmental disorders2020

Relationship Between Early Social-Emotional Behavior and Autism Spectrum Disorder: A High-Risk Sibling Study.

Sarah Raza, Lori-Ann R Sacrey, Lonnie Zwaigenbaum, Susan Bryson, Jessica Brian, Isabel M Smith, Wendy Roberts, Peter Szatmari, Tracy Vaillancourt, Caroline Roncadin and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Emotion dysregulation in autism: Severity and correlates in early childhood.Autism research : official journal of the International Society for Autism Research · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Attend Less, Fear More: Elevated Distress to Social Threat in Toddlers With Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah RazaDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada. sraza@ualberta.ca.ORCID http://orcid.org/0000-0002-3666-8585
Lori-Ann R SacreyDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Susan BrysonDalhousie University/IWK Health Centre, Halifax, NS, Canada.
Jessica BrianBloorview Research Institute, Toronto, ON, Canada.
Isabel M SmithDalhousie University/IWK Health Centre, Halifax, NS, Canada.
Wendy RobertsISAND, Toronto, ON, Canada.
Peter SzatmariUniversity of Toronto, Toronto, ON, Canada.
Tracy VaillancourtUniversity of Ottawa, Ottawa, ON, Canada.
Caroline RoncadinMcMaster Children's Hospital - Hamilton Health Sciences, Hamilton, ON, Canada.
Nancy GaronMount Allison University, Sackville, NB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Social-emotional behavior in autism spectrum disorder (ASD) was examined among high-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers. Caregivers completed the Infant-Toddler Social Emotional Assessment (ITSEA) at 18 months, and blind diagnostic assessment for ASD was conducted at 36 months. Results indicated impairment in social-emotional functioning among HR toddlers subsequently diagnosed with ASD compared to other HR and LR toddlers, such that ITSEA domains (Internalizing, Dysregulation, Competence) and subdomains predicted later ASD symptoms and diagnosis. Receiver operating curves of optimal ITSEA cutoffs ranged from 0.23 to 0.44 for sensitivity, and 0.74 to 0.89 for specificity. Although classification accuracy for ASD was limited, group differences highlight the importance of considering social-emotional development when assessing ASD risk.

Indexed as

Social BehaviorAutism Spectrum DisorderCanadaChild, PreschoolEmotionsFemaleFollow-Up StudiesHumansInfantMaleMass ScreeningProspective StudiesRisk AssessmentSiblingsAutismAutism spectrum disorderEarly detectionHigh-risk infant siblingsSocial-emotional behavior

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.