Evidence map›Paper›PMID 30852734›Full record

ArticleInternational ophthalmology2019

Bartonella henselae- and quintana-associated uveitis: a case series and approach of a potentially severe disease with a broad spectrum of ocular manifestations.

Dimitrios Kalogeropoulos, Ioannis Asproudis, Maria Stefaniotou, Marilita M Moschos, Andreas Mentis, Konstantinos Malamos, Chris Kalogeropoulos

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Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Atypical Presentations and Molecular Diagnosis of Ocular Bartonellosis.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Article
  4. Frontiers in psychiatry · 2024
    Article
  5. Article
  6. Article
  7. Pediatric Bartonella henselae neuroretinitis masking co-infections.American journal of ophthalmology case reports · 2022
    Article
  8. Article
  9. Open forum infectious diseases · 2021
    Article
  10. Article
  11. Human Bartonellosis: An Underappreciated Public Health Problem?Tropical medicine and infectious disease · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dimitrios KalogeropoulosDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece. dkalog1990@gmail.com.ORCID http://orcid.org/0000-0001-6404-5409
Ioannis AsproudisDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.
Maria StefaniotouDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.
Marilita M MoschosFirst Department of Ophthalmology, General Hospital of Athens G. Gennimatas, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Andreas MentisLaboratory of Medical Microbiology, Hellenic Pasteur Institute, Athens, Greece.
Konstantinos MalamosDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.
Chris KalogeropoulosDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece. kalogch@otenet.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the clinical manifestations of intraocular inflammation associated with Bartonella infection and describe the assessment and management of patients with cat-scratch disease (CSD).

methodsThis is a retrospective review of the clinical records of patients diagnosed with Bartonella henselae and Bartonella quintana intraocular inflammation from 2011 to 2018 in the Department of Ocular Inflammations and Infections of the University Eye Clinic of Ioannina (Greece). An analysis of the current literature concerning Bartonella-related intraocular infections was also carried out.

resultsThis is a retrospective study of 13 patients (7 males and 6 females) with a mean age of 39.2 years that were diagnosed with unilateral intraocular inflammation, except one case with bilateral affection, attributed to Bartonella (either henselae or quintana). Twelve (12) patients (92.3%) had a positive history of traumatic cat contact. The main ocular clinical findings with regard to the type of uveitis included neuroretinitis in 5 eyes (38.5%), vasculitis in 3 eyes (23.1%), iridocyclitis in 2 eyes (15.4%), intermediate uveitis in 2 eyes (15.4%), posterior uveitis in 1 eye (7.7%), panuveitis in 2 eyes (15.4%), retinochoroiditis in 2 eyes (15.4%), vitritis in 1 eye (7.7%), peripheral choroidal granuloma in 1 eye (7.7%). Immunoglobulin (Ig) G was positive in all cases. All patients were treated with antibiotics (mainly rifampicin, doxycycline and azithromycin). The visual acuity was noted to be improved in all patients after treatment, but some of them experienced disturbing complications.

conclusionCSD may manifest with various ocular pathological findings. Taking into consideration the increasing frequency of infections by B. henselae and B. quintana, clinicians should always incorporate CSD in the differential diagnosis of such presentations of uveitis. Educating vulnerable groups (children, immunosuppressed, etc.) and also general population, the appropriate preventing measures can contribute in limiting the risk of infection.

Indexed as

AdolescentAdultAgedBartonella henselaeBartonella quintanaCat-Scratch DiseaseChildChoroidDiagnosis, DifferentialEye Infections, BacterialFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleBartonellaCat-scratch diseaseChoroidal granulomaEndophthalmitisNeuroretinitisOptic neuropathyRetinal vasculitis/vascular occlusionRetinochoroiditisUveitis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.