Evidence map›Paper›PMID 30852710›Full record

ReviewCurrent psychiatry reports2019

Phenibut (β-Phenyl-γ-Aminobutyric Acid): an Easily Obtainable "Dietary Supplement" With Propensities for Physical Dependence and Addiction.

Edward A Jouney

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Phenibut: A drug with one too many "buts".Basic & clinical pharmacology & toxicology · 2024
    Review
  3. Review
  4. Article
  5. A case of phenibut withdrawal and treatment with baclofen.World journal of emergency medicine · 2023
    Article
  6. GABACurrent topics in behavioral neurosciences · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Interpol review of controlled substances 2016-2019.Forensic science international. Synergy · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Edward A JouneyDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA. ejouney@med.umich.edu.
University of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPhenibut (β-phenyl-γ-aminobutyric acid) is a psychoactive GABA analogue currently being marketed online as an anxiolytic and nootropic dietary supplement. Its use is growing in popularity, but its pharmacological activity is well beyond that of a conventional nutritional supplement, and similar to that of a prescription strength sedative. This review will focus on the potential adversities of phenibut use and will discuss what treatment options may be beneficial to afflicted patients. RECENT

findingsOver the last several years, multiple case reports have highlighted phenibut's potential to produce the conditions of physical dependence, withdrawal, and addiction. In cases involving intoxication, patients have presented with a varying degree of mental status changes, from being minimally responsive to manifesting symptoms of an agitated delirium. Phenibut is a potent psychoactive substance with GABA

Indexed as

Behavior, AddictiveDietary Supplementsgamma-Aminobutyric AcidHumansHypnotics and SedativesNootropic AgentsSubstance-Related Disorders4-amino-3-phenylbutyric acidgamma-Aminobutyric AcidHypnotics and SedativesNootropic AgentsBaclofenDietary supplementGABAB agonistNew psychoactive substanceNootropicPhenibut

Identifiers

PMID30852710
OpenAlexW2920872497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.