ArticleDysphagia2020
Progression of Oropharyngeal Dysphagia in Patients with Multiple System Atrophy.
Article in Dysphagia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Enteral Nutrition in Idiopathic Parkinson's Disease and Atypical Parkinsonism: A Systematic Review.Movement disorders clinical practice · 2026Pooled it
- Abnormal swallowing-breathing coordination is an electrokinesiographic feature of dysphagia in multiple system atrophy: a comparative study with Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Survival benefit of enteral nutrition and airway interventions in multiple system atrophy.Clinical parkinsonism & related disorders · 2026Article
- Early-onset dysphagia predicts short survival in multiple system atrophy.Journal of neurology · 2024Article
- Frequency and outcomes of gastrostomy insertion in a longitudinal cohort study of atypical parkinsonism.European journal of neurology · 2024Article
- Swallowing Characteristics in Patients with Multiple System Atrophy Analyzed Using FEES Examination.Dysphagia · 2024Article
- Cough Correlates of Functional Swallow Outcomes in Atypical Parkinsonism.Movement disorders clinical practice · 2024Article
- [Dysphagia in Parkinsonian Syndromes].Der Nervenarzt · 2023Review
- Multiple system atrophy.Practical neurology · 2023Review
- Pharyngolaryngeal semiology and prognostic factors in multiple system atrophy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Movement Disorders and the Gut: A Review.Movement disorders clinical practice · 2022Review
- Gastrointestinal dysfunction in the synucleinopathies.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021Review
- Current Management and Emerging Therapies in Multiple System Atrophy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Review
- Quipazine Elicits Swallowing in the Arterially Perfused Rat Preparation: A Role for Medullary Raphe Nuclei?International journal of molecular sciences · 2020Article
- Heightened risk of early vocal fold motion impairment onset and dysphagia in the parkinsonian variant of multiple system atrophy: a comparative study.Clinical parkinsonism & related disorders · 2020Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the progression of oropharyngeal dysphagia in patients with multiple system atrophy (MSA), with particular emphasis on MSA subtype variation. Fifty-nine MSA patients (31 MSA-P, 21 MSA-C, and 7 MSA-PC) who had undergone at least one videofluoroscopic swallowing study (VFSS) to evaluate dysphagia symptoms were included. Clinical data and VFSS findings were retrospectively evaluated using the videofluoroscopic dysphagia scale (VDS), and the results of each MSA subtype group were compared. The median latency to onset of diet modification from onset of MSA symptoms was 5.995 (95% CI 4.890-7.099) years in all MSA patients, 5.036 (95% CI 3.605-6.467) years in MSA-P, and 6.800 (95% CI 6.078-7.522) years in MSA-C (P = 0.035). The latency to onset of diet modification from onset of dysphagia symptoms was 2.715 (95% CI 2.132-3.298) years in all MSA patients, 2.299 (95% CI 1.194-3.403) years in MSA-P, and 5.074 (95% CI 2.565-7.583) years in MSA-C (P = 0.039). The latencies to onset of tube feeding from onset of MSA symptoms and dysphagia symptoms were 7.003 (95% CI 6.738-7.268) years and 3.515 (95% CI 2.123-4.907) years, respectively, in all MSA patients, without significant difference between subtypes. In the patients who underwent VFSS follow-up for ≥ 1 year, 6 oral VDS items significantly worsened; only two pharyngeal items exhibited significant changes. Patients with MSA-P commenced diet modification earlier than patients with MSA-C, despite no significant difference in the latency to onset of tube feeding. Deterioration of dysphagia may be more pronounced in the oral function of MSA patients.
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