Evidence map›Paper›PMID 30852628›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2019

Prostaglandin E

Peta Bradbury, Brijeshkumar S Patel, Aylin Cidem, Cassandra P Nader, Brian G Oliver, Alaina J Ammit

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peta BradburyWoolcock Emphysema Centre, Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia.
Brijeshkumar S PatelFaculty of Pharmacy, University of Sydney, Sydney, NSW, Australia.
Aylin CidemWoolcock Emphysema Centre, Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia.
Cassandra P NaderWoolcock Emphysema Centre, Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia.
Brian G OliverWoolcock Emphysema Centre, Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia.
Alaina J AmmitWoolcock Emphysema Centre, Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia. Alaina.Ammit@uts.edu.au.ORCID http://orcid.org/0000-0003-0555-2544
The University of Sydney · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tristetraprolin (TTP) is an anti-inflammatory molecule known to post-transcriptionally regulate cytokine production and is, therefore, an attractive drug target for chronic respiratory diseases driven by inflammation, such as asthma and chronic obstructive pulmonary disease. Our recent in vitro studies in primary human airway smooth (ASM) cells have confirmed the essential anti-inflammatory role played by TTP as a critical partner in a cytokine regulatory network. However, several unanswered questions remain. While prior in vitro studies have suggested that TTP is regulated in a cAMP-mediated manner, raising the possibility that this may be one of the ways in which β

Indexed as

Adrenergic beta-2 Receptor AgonistsAzetidinesBronchiCells, CulturedCyclic AMPDinoprostoneDual Specificity Phosphatase 1Formoterol FumarateHumansIsoindolesMyocytes, Smooth Musclep38 Mitogen-Activated Protein KinasesReceptors, Prostaglandin E, EP2 SubtypeRNA, MessengerSalmeterol XinafoateSulfonamides1-(4-fluorobenzoyl)-3-(((6-methoxy-2-naphthyl)oxy)methyl)azetidine-3-carboxylic acidAdrenergic beta-2 Receptor AgonistsAzetidinesCyclic AMPDinoprostoneDual Specificity Phosphatase 1DUSP1 protein, humanFormoterol FumarateIsoindolesN-(2-(4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo(f)isoindol-2-yl)phenyl)acetyl)benzene sulphonamidep38 Mitogen-Activated Protein KinasesReceptors, Prostaglandin E, EP2 SubtypeRNA, MessengerSalmeterol XinafoateSulfonamidesTristetraprolinAsthmacAMPCOPDInflammationPGE2Tristetraprolinβ2-agonists

Identifiers

PMID30852628
OpenAlexW2921525786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.