Evidence map›Paper›PMID 30852531›Full record

ArticleBMJ open2019

Ethnic variations in risk of preterm birth in an ethnically dense socially disadvantaged area in the UK: a retrospective cross-sectional study.

Shuby Puthussery, Leah Li, Pei-Ching Tseng, Lesley Kilby, Jogesh Kapadia, Thomas Puthusserry, Amardeep Thind

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shuby PuthusseryMaternal and Child Health Research Centre, Institute for Health Research, University of Bedfordshire, Luton, UK.ORCID 0000-0002-1865-9546
Leah LiPopulation, Policy and Practice Programme, Great Ormond Street Institute of Child Health, University College London, London, UK.ORCID 0000-0002-3603-6457
Pei-Ching TsengMaternal and Child Health Research Centre, Institute for Health Research, University of Bedfordshire, Luton, UK.
Lesley KilbyNeonatal Unit, Luton and Dunstable University Hospital NHS Foundation Trust, Luton, UK.
Jogesh KapadiaNeonatal Unit, Luton and Dunstable University Hospital NHS Foundation Trust, Luton, UK.
Thomas PuthusserryIndependent Consultant, London, UK.
Amardeep ThindSchulich School of Medicine and Dentistry, University of Western Ontario, London, Canada.
Luton and Dunstable University Hospital NHS Foundation Trust · GBUniversity of Bedfordshire · GBGreat Ormond Street Hospital · GBWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate ethnic variations in risk of preterm birth (PTB), including extreme preterm birth (EPTB) and moderately preterm birth (MPTB), among mothers in an ethnically dense, socially disadvantaged area, and to examine whether any variations were dependent of area deprivation and maternal biological and behavioural factors.

designRetrospective cross-sectional study using routinely collected data.

settingA large UK National Health Service maternity unit.

participants46 307 women who gave singleton births between April 2007 and March 2016. OUTCOME MEASURES: PTB defined as <37 weeks of gestation and further classified into EPTB (<28 weeks of gestation) and MPTB (28 to <37 weeks of gestation).

resultsOverall prevalence of PTB was higher (8.3%) compared with the national average (7.8%). Black Caribbean (2.2%) and black African (2.0%) mothers had higher absolute risk of EPTB than white British mothers (1.3%), particularly black Caribbean mothers whose relative risk ratio (RRR) was nearly twice after adjustment for all covariates (RRR=1.93[1.20 to 3.10]). Excess relative risk of EPTB among black African mothers became non-significant after adjustment for prenatal behavioural factors (RRR=1.41[0.99 to 2.01]). Bangladeshi mothers had the lowest absolute risk of EPTB (0.6%), substantially lower than white British mothers (1.3%); the difference in relative risk remained significant after adjustment for area deprivation (RRR=0.59[0.36 to 0.96]), but became non-significant after adjustment for maternal biological factors. Changes were evident in the relative risk of EPTB and MPTB among some ethnic groups compared with the white British on adjustment for different covariates.

conclusionsHigher than national rates of PTB point to the need for evidence-based antenatal and neonatal care programmes to support preterm babies and their families in ethnically dense socially disadvantaged areas. Differential impact of area deprivation and the role of modifiable behavioural factors highlight the need for targeted preventive interventions for groups at risk.

Indexed as

Gestational AgeMothersAdolescentAdultAsian PeopleBlack PeopleCross-Sectional StudiesEnglandFemaleHumansInfantInfant MortalityInfant, NewbornLogistic ModelsMaleParturitioncommunity child healthneonatologypublic health

Identifiers

PMID30852531
PMCPMC6429724
OpenAlexW2922413169

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.