Evidence map›Paper›PMID 30852156›Full record

ArticleBrazilian journal of otorhinolaryngology

Surgical outcomes of sinonasal inverted papilloma: a 17 year review.

Gil Coutinho, Joana Marques, Manuel Leal, Jorge Spratley, Margarida Sá Fernandes, Margarida Santos

Open access · goldAbstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 32 citations in OpenAlex.

  1. The characteristics of sinonasal inverted papilloma and recurrence factors: An analysis of 207 cases.World journal of otorhinolaryngology - head and neck surgery · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. The implications of concomitant mucosal inflammation on clinical manifestations and outcomes of sinonasal inverted papilloma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Gil CoutinhoCentro Hospitalar São João, Departamento de Otorrinolaringologia, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Unidade de Otorrinolaringologia, Porto, Portugal. Electronic address: gilcoutinho@med.up.pt.
Joana MarquesCentro Hospitalar São João, Departamento de Otorrinolaringologia, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Unidade de Otorrinolaringologia, Porto, Portugal.
Manuel LealCentro Hospitalar São João, Departamento de Otorrinolaringologia, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Unidade de Otorrinolaringologia, Porto, Portugal.
Jorge SpratleyCentro Hospitalar São João, Departamento de Otorrinolaringologia, Porto, Portugal; Faculdade de Medicina da Universidade do Porto, Unidade de Otorrinolaringologia, Porto, Portugal; Centro de Investigação em Tecnologia e Serviços de Saúde (CINTESIS), Porto, Portugal.
Margarida Sá FernandesCentro Hospitalar São João, Departamento de Patologia, Porto, Portugal; Universidade do Porto, Faculdade de Medicina, Departamento de Patologia, Porto, Portugal.
Margarida SantosCentro Hospitalar São João, Departamento de Otorrinolaringologia, Porto, Portugal.
Universidade do Porto · PTHospital de São João · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInverted papillomas represent one of the most common benign neoplasic lesions located in the sinonasal tract. Owing to the local erosive behavior, tendency to recur and the potential for malignant transformation, surgical management of inverted papillomas is often challenging.

objectiveThis study aimed to analyze the surgical outcomes of patients with inverted papillomas, according to the Krouse staging and the different surgical approaches.

methodsRetrospective study of patients diagnosed with sinonasal inverted papillomas who underwent surgical treatment between 2000 and 2016 at a tertiary referral hospital. Cases with follow-up less than 12 months were excluded. The rate and the time of recurrence were the main outcomes. Values of p<0.05 were considered statistically significant.

resultsThirty-six cases with mean age of 60 years, predominantly male (72%), were included. The follow-up period ranged from 1 to 16 years, with an average of 4.5 years. Krouse T1 Stage corresponded to 11.1%; T2 occurred in 50% of cases; while T3 and T4 Stages accounted for 30.6% and 8.3% of patients, respectively. Most cases were approached by an endoscopic technique alone (83.3%), with a recurrence rate of 13.3%. Patients treated via a combined or open approach revealed a recurrence of 16.7%. No differences in the recurrence rate were reported when comparing endoscopic surgery with the open or combined techniques. Krouse Stage T3 had a significant association with inverted papillomas recurrence (p=0.023). All inverted papilloma relapses occurred up to 2 years post-operatively. One case of malignant transformation was recorded (2.7%).

conclusionEndoscopic surgery did not increase the recurrence rates and can be a safe and efficient alternative to open or combined techniques. The recurrence of inverted papillomas seem to be related to the persistence of the disease and tend to occur early after primary surgery. Krouse T3 Stages may be associated with a higher recurrence of inverted papillomas.

Indexed as

AdultAgedAged, 80 and overEndoscopyFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPapilloma, InvertedParanasal Sinus NeoplasmsRetrospective StudiesYoung AdultEndoscopiaEndoscopyInverted papillomaPapiloma invertidoRecorrênciaRecurrenceResultado do tratamentoTreatment outcome

Identifiers

PMID30852156
PMCPMC9422424
OpenAlexW2916036130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.