Evidence map›Paper›PMID 30851879›Full record

Trial reportLancet (London, England)2019

Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial.

Maud Robert, Philippe Espalieu, Elise Pelascini, Robert Caiazzo, Adrien Sterkers, Lita Khamphommala, Tigran Poghosyan, Jean-Marc Chevallier, Vincent Malherbe, Elie Chouillard and 8 more

Erratum issued Registry-linked trialOpen access · bronzeAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lancet (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02139813 (Prospective Multicentric Randomized Trial of Efficiency and Safety of Laparoscopic Omega Loop Bypass Versus Roux-en-Y Gastric Bypass), which is not on this map. Cited by 200 papers, 29 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
200citing papers in PubMed, 29 pooled it
51.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02139813 nacompletednot on this map

Prospective Multicentric Randomized Trial of Efficiency and Safety of Laparoscopic Omega Loop Bypass Versus Roux-en-Y Gastric Bypass

TypeinterventionalSponsorHospices Civils de LyonRan2014 to 2018Enrolled256ConditionsObesityArmsLaparoscopic Mini-gastric bypass, Procedure of reference in bariatric surgery
3 · Its place in the literature

Who cites it

200 citing papers in PubMed, 29 syntheses or guidelines pooled it, 466 citations in OpenAlex.

  1. Experienced Weight Stigma Changes Following Bariatric Surgery: a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  15. One Anastomosis Gastric Bypass Versus Sleeve Gastrectomy for Obesity: a Systemic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
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140 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 1 country.

Maud RobertDepartment of Digestive and Bariatric Surgery, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France; CarMeN Laboratory, Université Claude Bernard Lyon 1, INSERM 1060, Lyon, France. Electronic address: maud.robert@chu-lyon.fr.
Philippe EspalieuHôpital Privé de la Loire, Saint-Étienne, France.
Elise PelasciniDepartment of Digestive and Bariatric Surgery, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France.
Robert CaiazzoGeneral and Endocrine Surgery Department, Huriez Hospital, Lille, France; European Genomic Institute for Diabetes, Lille University, INSERM Lille, Lille, France.
Adrien SterkersDepartment of Digestive, Hepatobiliary Surgery, Centre Hospitalier Privé Saint Grégoire, Saint Gregoire, France.
Lita KhamphommalaDepartment of Digestive, Hepatobiliary Surgery, Centre Hospitalier Privé Saint Grégoire, Saint Gregoire, France.
Tigran PoghosyanDigestive Surgery Department, Hôpital Européen Georges Pompidou, Paris, France.
Jean-Marc ChevallierDigestive Surgery Department, Hôpital Européen Georges Pompidou, Paris, France.
Vincent MalherbeGeneral and Endocrine Surgery Department, Hôpital Privé Drôme et Ardèche, Guilherand-Granges, France.
Elie ChouillardDepartment of General and Digestive Surgery, Centre Hospitalier Intercommunal Poissy/Saint-Germain-en-Laye, Saint-Germain-en-Laye, France.
Fabian RecheDigestive Surgery Department, CHU Grenoble, Grenoble, France.
Adriana TorciviaDepartment of Digestive, Hepatobiliary Surgery, Hôpital Pitié Salpétrière, Paris, France.
Delphine Maucort-BoulchBiostatistics Department, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Benite, France.
Sylvie Bin-DorelClinical Research Unit, Hospices Civils de Lyon, Lyon, France.
Carole Langlois-JacquesBiostatistics Department, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Benite, France.
Dominique DelaunayDepartment of Digestive and Bariatric Surgery, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France.
François PattouGeneral and Endocrine Surgery Department, Huriez Hospital, Lille, France; European Genomic Institute for Diabetes, Lille University, INSERM Lille, Lille, France.
Emmanuel DisseCarMeN Laboratory, Université Claude Bernard Lyon 1, INSERM 1060, Lyon, France; Department of Endocrinology, Diabetology and Nutrition, Specialized Center for Obesity Management, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Benite, France.
Hospices Civils de Lyon · FRCentre Hospitalier privé Saint Grégoire · FRHôpital Edouard Herriot · FRHôpital Lyon Sud · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Intercommunal de Poissy · FRCentre Hospitalier Universitaire de Grenoble · FREuropean Genomic Institute for Diabetes · FRGénérale de Santé · FRHôpital Claude Huriez · FRHôpital Européen Georges-Pompidou · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne anastomosis gastric bypass (OAGB) is increasingly used in the treatment of morbid obesity. However, the efficacy and safety outcomes of this procedure remain debated. We report the results of a randomised trial (YOMEGA) comparing the outcomes of OAGB versus standard Roux-en-Y gastric bypass (RYGB).

methodsThis prospective, multicentre, randomised non-inferiority trial, was held in nine obesity centres in France. Patients were eligible for inclusion if their body-mass index (BMI) was 40 kg/m

findingsFrom May 13, 2014, to March 2, 2016, of 261 patients screened for eligibility, 253 (97%) were randomly assigned to OAGB (n=129) or RYGB (n=124). Five patients did not undergo their assigned surgery, and after undergoing their surgery 14 were excluded from the per-protocol analysis (seven due to pregnancy, two deaths, one withdrawal, and four revisions from OAGB to RYGB) In the per-protocol population (n=117 OAGB, n=117 RYGB), mean age was 43·5 years (SD 10·8), mean BMI was 43·9 kg/m

interpretationOAGB is not inferior to RYGB regarding weight loss and metabolic improvement at 2 years. Higher incidences of diarrhoea, steatorrhoea, and nutritional adverse events were observed with a 200 cm biliopancreatic limb OAGB, suggesting a malabsorptive effect.

fundingFrench Ministry of Health.

Indexed as

AdultAnastomosis, Roux-en-YAnastomosis, SurgicalBody Mass IndexDiarrheaFemaleFranceGastric BypassHumansMaleMetabolismMiddle AgedObesity, MorbidProspective StudiesSteatorrheaTreatment Outcome

Identifiers

PMID30851879
OpenAlexW2920729423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.