ArticleNeuroImage. Clinical2019
Cortical volume and 40-Hz auditory-steady-state responses in patients with schizophrenia and healthy controls.
Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Developmental and aging trajectories of 40-Hz auditory steady-state responses: A systematic review across the human lifespan.Developmental cognitive neuroscience · 2026Pooled it
- Effects of N-Methyl-d-Aspartate Receptor Antagonists on Gamma-Band Activity During Auditory Stimulation Compared With Electro/Magneto-encephalographic Data in Schizophrenia and Early-Stage Psychosis: A Systematic Review and Perspective.Schizophrenia bulletin · 2024Pooled it
- Disruption of brain rhythms in a pharmacological model of schizophrenia in male and female mice.Biology of sex differences · 2025Article
- Sex differences in the lateralization of sustained electrophysiological response to 40 Hz clicks in typically developing preschoolers.Scientific reports · 2025Article
- Phase Locking of 40 Hz Auditory Steady State Responses Is Modulated by Sensory Predictability and Linked to Cerebellar Myelination.Human brain mapping · 2025Article
- Influence of genetic polymorphism and trauma on cortical structures and PTSD severity: Imaging genetics generalized structured component analysis.Frontiers in psychiatry · 2025Article
- Auditory Steady-State Responses in Schizophrenia: An Updated Meta-Analysis.Brain sciences · 2023Review
- Influence of inter-stimulus interval on 40-Hz auditory steady-state response in patients with schizophrenia.Schizophrenia (Heidelberg, Germany) · 2023Article
- Phase Delay of the 40 Hz Auditory Steady-State Response Localizes to Left Auditory Cortex in Schizophrenia.Clinical EEG and neuroscience · 2023Article
- The decoupling of structural and functional connectivity of auditory networks in individuals at clinical high-risk for psychosis.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2023Article
- Cortical connectomic mediations on gamma band synchronization in schizophrenia.Translational psychiatry · 2023Article
- Responses at Individual Gamma Frequencies Are Related to the Processing Speed but Not the Inhibitory Control.Journal of personalized medicine · 2022Article
- Gamma-band entrainment abnormalities in schizophrenia: Modality-specific or cortex-wide impairment?Journal of psychopathology and clinical science · 2022Article
- Auditory driven gamma synchrony is associated with cortical thickness in widespread cortical areas.NeuroImage · 2022Article
- The Full Informational Spectral Analysis for Auditory Steady-State Responses in Human Brain Using the Combination of Canonical Correlation Analysis and Holo-Hilbert Spectral Analysis.Journal of clinical medicine · 2022Article
- Improved cognitive function in patients with major depressive disorder after treatment with vortioxetine: A EEG study.Neuropsychopharmacology reports · 2022Article
- Individual Resonant Frequencies at Low-Gamma Range and Cognitive Processing Speed.Journal of personalized medicine · 2021Article
- Gamma-Range Auditory Steady-State Responses and Cognitive Performance: A Systematic Review.Brain sciences · 2021Review
- Envelope Following Response to 440 Hz Carrier Chirp-Modulated Tones Show Clinically Relevant Changes in Schizophrenia.Brain sciences · 2020Article
- A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
Corrections and comments
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAbnormalities in the 40-Hz auditory steady-state response (ASSR) of the gamma range have been reported in schizophrenia (SZ) and are regarded as important pathophysiological features. Many of the previous studies reported diminished gamma oscillations in SZ, although some studies reported increased spontaneous gamma oscillations. Furthermore, brain morphological correlates of the gamma band ASSR deficits have rarely examined. We investigated different measures of the 40-Hz ASSR and their association with brain volumes and psychological measures of SZ.
methodsThe 40-Hz ASSR was measured for 80 dB click sounds (1 ms, 500-ms trains at 40-Hz, with 3050 to 3500 inter-train interval) using electroencephalography with 64 electrodes in 33 patients with SZ (male: 16, female: 17 (age range: 21-60)) and 30 healthy controls (HCs) (male: 13, female: 17 (age range: 23-64)). Four gamma oscillation measures (evoked power, spontaneous oscillations (baseline and total power), and inter-trial phase coherence (ITC)) were assessed. The source activities of the ASSR were also analyzed. Brain volumes were assessed using high-resolution magnetic resonance imaging and voxel-based morphometry and superior temporal gyrus (STG) volume measures were obtained.
resultsPatients with SZ had larger total and evoked powers and higher ITC than HCs. Both groups showed significantly different association between mean evoked power and right STG volume. In HCs but not SZ, mean evoked power showed significant positive correlation with right STG volume. In addition, the two groups showed significantly different association between verbal fluency and mean evoked power. High evoked power was significantly correlated with poor verbal fluency in SZ.
conclusionsThe current study found increased gamma oscillation in SZ and suggests significant involvement of the STG in gamma oscillations.
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