Evidence map›Paper›PMID 30851396›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2019

Longitudinal Associations Between Sleep Patterns and Psychiatric Symptom Severity in High-Risk and Community Comparison Youth.

Adriane M Soehner, Michele A Bertocci, Jessica C Levenson, Tina R Goldstein, Brian Rooks, John Merranko, Danella Hafeman, Rasim Diler, David Axelson, Benjamin I Goldstein and 4 more

Abstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Association between early childhood sleep difficulties and subsequent psychiatric illness.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  8. Development of morning-eveningness in adolescence: implications for brain development and psychopathology.Journal of child psychology and psychiatry, and allied disciplines · 2023
    Article
  9. Factors Associated With Sleep Disturbance Amongst Youth With Bipolar Disorder.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Sleep and Mood Disorders Among Youth.Child and adolescent psychiatric clinics of North America · 2021
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Adriane M SoehnerUniversity of Pittsburgh, PA. Electronic address: soehneram2@upmc.edu.
Michele A BertocciUniversity of Pittsburgh, PA.
Jessica C LevensonUniversity of Pittsburgh, PA.
Tina R GoldsteinUniversity of Pittsburgh, PA.
Brian RooksUniversity of Pittsburgh, PA.
John MerrankoUniversity of Pittsburgh, PA.
Danella HafemanUniversity of Pittsburgh, PA.
Rasim DilerUniversity of Pittsburgh, PA.
David AxelsonNationwide Children's Hospital and Ohio State University, Columbus, OH.
Benjamin I GoldsteinSunnybrook Health Sciences Centre, Toronto, Ontario, CA; University of Toronto, Ontario, CA.
Mary Beth HickeyUniversity of Pittsburgh, PA.
Kelly MonkUniversity of Pittsburgh, PA.
Mary L PhillipsUniversity of Pittsburgh, PA.
Boris BirmaherUniversity of Pittsburgh, PA.

Funding

Subject Management and BiobankingP50DA046346 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PETER L FRANZEN · 2020 to 2026
$23.4M
Children of Bipolar Parents: A High Risk Follow Up Study (also known as Bipolar Offspring Study - BIOS)R01MH060952 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS, PHILLIPS, MARY LOUISE · 2001 to 2020
$20.4M
Vulnerability to Bipolar Disorder in Adolescence: Interactions Among Sleep Variability, Familial Risk, and Reward-Control ProcessesK01MH111953 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SOEHNER, ADRIANE M. · 2016 to 2020
$803k
Targeted Intervention for Insufficient Sleep among Typically-Developing AdolescentsK23HD087433 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEVENSON, JESSICA C · 2017 to 2021
$670k
NICHD NIH HHS K23 HD087433NIDA NIH HHS P50 DA046346NIMH NIH HHS K01 MH111953NIMH NIH HHS R01 MH060952
6 · The paper itself

Abstract

objectiveSleep disturbance may be involved in symptom progression across multiple domains of psychopathology and could represent a target for treatment development in youth. Our objective was to identify sleep patterns that longitudinally change in conjunction with psychiatric symptom severity in at-risk youth.

methodThe study included 484 Pittsburgh Bipolar Offspring Study (BIOS) youth with at least 2 sleep assessments occurring between 10 and 18 years of age: 267 offspring of parents with bipolar I or II disorder and 217 community comparison offspring. Assessments occurred approximately every 2 years (mean number of assessments, 2.8 ± 0.8; mean follow-up duration, 3.8 ± 1.6 years). Offspring had a range of psychiatric diagnoses at baseline. Multivariate lasso regression was implemented to select offspring-reported sleep patterns associated with changes in five psychiatric symptom measures from baseline through last follow-up (mania, depression, mood lability, anxiety, inattention/externalizing). Analyses accounted for parent psychiatric diagnoses and offspring demographics, psychiatric diagnoses, and medications.

resultsFollow-up duration, baseline socioeconomic status, parental history of bipolar disorder, offspring attention-deficit/hyperactivity disorder, and disruptive behavior disorder, and five sleep patterns were identified as predictors of change in all five psychiatric symptom measures. Decreasing sleep duration, later sleep timing preference, longer sleep latency, increasing nighttime awakenings, and greater sleepiness over follow-up were associated with increasing severity the five psychiatric symptom outcomes over follow-up. These 10 predictors explained 16% of the variance in longitudinal psychiatric symptom change, 33% of which was accounted for by sleep predictors.

conclusionA constellation of sleep features were associated with psychiatric symptom changes in youth, and may represent viable targets for future interventions.

Indexed as

AdolescentAttention Deficit Disorder with HyperactivityBipolar DisorderChildChild of Impaired ParentsFamily HealthFemaleHumansLongitudinal StudiesMaleParentsPsychiatric Status Rating ScalesPsychopathologySleep Wake Disorderscircadianlongitudinalpsychiatric symptomssleepyouth

Identifiers

PMID30851396
PMCPMC6733405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.