Evidence map›Paper›PMID 30851239›Full record

ArticleChemico-biological interactions2019

Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells.

Georgia Charkoftaki, David C Thompson, Jaya Prakash Golla, Rolando Garcia-Milian, TuKiet T Lam, Jasper Engel, Vasilis Vasiliou

Open access · greenAbstract read
In one paragraph

Article in Chemico-biological interactions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. The Significance of Aldehyde Dehydrogenase 1 in Cancers.International journal of molecular sciences · 2024
    Review
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Georgia CharkoftakiDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, CT, 06520, USA.
David C ThompsonDepartment of Clinical Pharmacy, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA.
Jaya Prakash GollaDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, CT, 06520, USA.
Rolando Garcia-MilianBioinformatics Support Program, Cushing/Whitney Medical Library, Yale School of Medicine, New Haven, CT, 06250, USA.
TuKiet T LamDepartment of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, 06510, USA; Yale MS & Proteomics Resource, WM Keck Biotechnology Resource Laboratory, New Haven, CT, 06510, USA.
Jasper EngelBiometris, Wageningen University & Research, Wagenigen, the Netherlands.
Vasilis VasiliouDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, CT, 06520, USA. Electronic address: vasilis.vasiliou@yale.edu.
Yale University · USUniversity of Colorado Anschutz Medical Campus · USWageningen University & Research · NLWhitney Museum of American Art · USW. M. Keck Foundation · US

Funding

Mouse Models for Alcohol Metabolism and Tissue InjuryR24AA022057 · NIAAA · YALE UNIVERSITY · PI VASILIOU, VASILIS · 2013 to 2022
$4.5M
Novel Role of Corneal Crystallins as Modulators of Cell Growth and TransparencyR01EY017963 · NEI · YALE UNIVERSITY · PI VASILIOU, VASILIS · 2007 to 2019
$3.7M
The role of ALDH1B1 in ethanol metabolism and colon cancerU01AA021724 · NIAAA · YALE UNIVERSITY · PI VASILIOU, VASILIS · 2014 to 2017
$1.7M
6500 QTrap Mass Spectrometer for Yale UniversityS10OD018034 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2014 to 2014
$514k
The role of ALDH1B1 in ethanol metabolism and colon cancerR01AA021724 · NIAAA · YALE UNIVERSITY · PI VASILIOU, VASILIS · 2018 to 2018
$397k
NEI NIH HHS R01 EY017963NIAAA NIH HHS R01 AA021724NIAAA NIH HHS R24 AA022057NIAAA NIH HHS U01 AA021724NIH HHS S10 OD018034
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MetabolomicsProteomicsAldehyde DehydrogenaseAldehyde Dehydrogenase 1 FamilyCell Line, TumorCluster AnalysisColonic NeoplasmsHumansLipid MetabolismMetabolomePrincipal Component AnalysisProteomeRetinal DehydrogenaseRNARNA InterferenceRNA, Small InterferingAldehyde DehydrogenaseAldehyde Dehydrogenase 1 FamilyALDH1A1 protein, humanProteomeRetinal DehydrogenaseRNARNA, Small Interfering

Identifiers

PMID30851239
PMCPMC7988342
OpenAlexW2921358557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.