ReviewJournal of thrombosis and haemostasis : JTH2019
Reducing the hospital burden associated with the treatment of pulmonary embolism.
Review in Journal of thrombosis and haemostasis : JTH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism.Blood advances · 2020Guideline
- Comprehensive Outpatient Management of Low-Risk Pulmonary Embolism: Can Primary Care Do This? A Narrative Review.The Permanente journal · 2020Pooled it
- Impact of chest pain on mortality in patients with acute pulmonary embolism.Scientific reports · 2024Article
- The Clinical Impact of the Pulmonary Embolism Severity Index on the Length of Hospital Stay of Patients with Pulmonary Embolism: A Randomized Controlled Trial.Diagnostics (Basel, Switzerland) · 2024Article
- Home Treatment for Low-risk Pulmonary Embolism: Is it Happening?Journal of community hospital internal medicine perspectives · 2024Article
- Validation of the HULL Score clinical prediction rule for unsuspected pulmonary embolism in ambulatory cancer patients.ERJ open research · 2023Article
- Management and Outcomes of Adults Diagnosed with Acute Pulmonary Embolism in Primary Care: Community-Based Retrospective Cohort Study.Journal of general internal medicine · 2022Article
- Risk stratification for clinical severity of pulmonary embolism in patients with cancer: a narrative review and MASCC clinical guidance for daily care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Review
- Sustainability of a Clinical Decision Support Intervention for Outpatient Care for Emergency Department Patients With Acute Pulmonary Embolism.JAMA network open · 2022Article
- Effect of Prognostic Guided Management of Patients With Acute Pulmonary Embolism According to the European Society of Cardiology Risk Stratification Model.Frontiers in cardiovascular medicine · 2022Article
- Challenges in Managing Isolated Subsegmental Pulmonary Embolism.The Permanente journal · 2021Article
- A clinical decision framework to guide the outpatient treatment of emergency department patients diagnosed with acute pulmonary embolism or deep vein thrombosis: Results from a multidisciplinary consensus panel.Journal of the American College of Emergency Physicians open · 2021Article
- "Outpatient Management" of Pulmonary Embolism Defined in the Primary Literature: A Narrative Review.The Permanente journal · 2021Review
- Clinical factors associated with massive pulmonary embolism and PE-related adverse clinical events.International journal of cardiology · 2021Article
- Primary care physicians comprehensively manage acute pulmonary embolism without higher-level-of-care transfer: A report of two cases.Medicine · 2020Article
- Managing acute pulmonary embolism in primary care in a patient declining emergency department transfer: a case report.European heart journal. Case reports · 2020Article
- Listen to Your Heart (but DON'T Look at Theirs): Risk Assessment for Home Treatment of Pulmonary Embolism.American journal of respiratory and critical care medicine · 2020Article
- Reducing the hospital burden associated with the treatment of pulmonary embolism.Journal of thrombosis and haemostasis : JTH · 2019Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Pulmonary embolism (PE) is the most feared clinical presentation of venous thromboembolism (VTE). Patients with PE have traditionally been treated in hospital; however, many are at low risk of adverse outcomes and current guidelines suggest outpatient treatment as an option. Outpatient treatment of PE offers several advantages, including reduced risk of hospital-acquired conditions and potential cost savings. Despite this, patients with low-risk PE are still frequently hospitalized for treatment. This narrative review summarizes current guideline recommendations for the identification of patients with low-risk PE who are potentially suitable for outpatient treatment, using prognostic assessment tools (e.g. the Pulmonary Embolism Severity Index [PESI] and simplified PESI) and clinical exclusion criteria (e.g. Hestia criteria) alone or in combination with additional cardiac assessments. Treatment options are discussed along with recommendations for the follow-up of patients managed in the non-hospital environment. The available data on outpatient treatment of PE are summarized, including details on patient selection, anticoagulant choice, and short-term outcomes in each study. Accumulating evidence suggests that outcomes in patients with low-risk PE treated as outpatients are at least as good as, if not better than, those of patients treated in the hospital. With mounting pressures on health care systems worldwide, increasing the proportion of patients with PE treated as outpatients has the potential to reduce health care burdens associated with VTE.
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