ArticleAddiction (Abingdon, England)2019
Medical complications associated with substance use disorders in patients with type 2 diabetes and hypertension: electronic health record findings.
Article in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Proposing a "Brain Health Checkup (BHC)" as a Global Potential "Standard of Care" to Overcome Reward Dysregulation in Primary Care Medicine: Coupling Genetic Risk Testing and Induction of "Dopamine Homeostasis".International journal of environmental research and public health · 2022Pooled it
- A Stacked Ensemble Multi-Label Model for Predicting Co-Occurring Microvascular and Macrovascular Complications in Type 2 Diabetes.Chronic diseases and translational medicine · 2026Article
- GLP-1 Receptor Agonist Treatment and Health Outcomes in Methadone-Treated Patients with Opioid Use Disorder and Diabetes.Journal of general internal medicine · 2026Article
- Chronic Disease Management Among People Treated for Comorbid Serious Mental Illness and/or Substance Use Disorders: A Population-Based Observational Study.Community mental health journal · 2026Article
- A Systematic Review of Treatment Approaches for Individuals With Coexisting Diabetes and Substance Use Disorder.Cureus · 2025Review
- Amputation trends among people who use drugs in the context of Philadelphia's increasingly xylazine adulterated drug supply.Drug and alcohol dependence · 2025Article
- Type 2 Diabetes Health Care Outcomes for Patients with Alcohol Use Disorder Starting Addiction Treatment.Journal of general internal medicine · 2025Article
- Global and regional burden of four drug use disorders in the elderly, 1990 to 2021: an analysis of the global burden of disease study.BMC geriatrics · 2025Article
- Associations of Co-Occurring Substance Use Disorder With Diabetes Care Quality, Complications, and Hospitalizations.Medical care · 2025Article
- The interface of depression and diabetes: treatment considerations.Translational psychiatry · 2025Review
- Trends and Inequalities in Diabetes-Related Complications Among U.S. Adults, 2000-2020.Diabetes care · 2025Article
- Cannabis Use and Clinical Outcomes in Adolescents and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study.Diabetes spectrum : a publication of the American Diabetes Association · 2025Article
- Relationship between Diabetes with Drug Use, Family History and Alcohol; Insights from the PERSIAN Cohort Study for Health Service Management :.Galen medical journal · 2025Article
- Article
- Regular cannabis smoking and carotid artery calcification in the Multi-Ethnic Study of Atherosclerosis (MESA).Vascular medicine (London, England) · 2024Article
- Is alcohol use disorder associated with higher rates of depression and anxiety among people with new onset type 2 diabetes? A cohort study using linked primary care data in England.BMC primary care · 2024Article
- When the Going Gets Tough: Multimorbidity and Heavy and Binge Drinking Among Adults.American journal of preventive medicine · 2024Article
- Comorbidity Burden and Health Care Utilization by Substance use Disorder Patterns among People with HIV in Florida.AIDS and behavior · 2024Article
- At-Risk Drinking in US Adults with Health Conditions: Differences by Gender, Race, and Ethnicity in the National Survey of Drug Use and Health, 2015-2019.Journal of racial and ethnic health disparities · 2024Article
- Exploring Health Informatics in the Battle against Drug Addiction: Digital Solutions for the Rising Concern.Journal of personalized medicine · 2024Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
aimsScreening for substance use disorder (SUD) in general medical settings may be particularly important in patients with comorbid health conditions exacerbated by SUD. This study evaluated whether SUD is associated with type 2 diabetes mellitus (T2DM) complications in patients with co-occurring T2DM and hypertension.
designAnalysis of a limited data set obtained through IBM Watson Health Explorys, a platform integrating data from electronic health records. Matched controls were defined for each of five SUDs: tobacco use disorder (TUD), opioid use disorder (OUD), cocaine use disorder, cannabis use disorder (CUD) and alcohol use disorder (AUD) using Mahalanobis distance within propensity score calipers.
settingAll patients were seen in the MetroHealth System (Cleveland, OH, USA) and had diagnosis codes for T2DM and hypertension.
participantsSUD group participants had a diagnosis of abuse/dependence for the substance of interest. Controls for each SUD group had no diagnosis code related to the SUD of interest and were selected to match the SUD patients on demographics, residential zip code median income and body mass index. Total sample sizes for each SUD-control comparison ranged from 1160 for CUD to 22 128 for TUD. MEASUREMENTS: Outcome was diagnosis (yes/no) of four T2DM complications (cerebrovascular accident, diabetic neuropathy, diabetic renal disease, myocardial infarction) and all-cause mortality.
findingsLogistic regressions revealed that SUD was significantly associated with greater risk of cerebrovascular accident [TUD odds ratio (OR) = 1.79, OUD-OR = 1.94, cocaine use disorder OR = 2.67], diabetic neuropathy [TUD-adjusted OR (aOR) = 1.47, cocaine use disorder-aOR = 1.35, AUD-aOR = 1.27], diabetic renal disease (TUD-aOR = 1.25, OUD-OR = 1.34), myocardial infarction (TUD-OR = 1.96, OUD-OR = 2.01, cocaine use disorder-OR = 2.68, CUD-OR = 2.48, AUD-OR = 1.42) and mortality (TUD-OR = 1.15, cocaine use disorder-OR = 1.61, CUD-OR = 1.49, AUD-OR = 1.35).
conclusionsAmong patients in Ohio USA with both type 2 diabetes mellitus (T2DM) and hypertension, those with substance use disorders appear to have greater risk for T2DM complications and all-cause mortality.
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