Evidence map›Paper›PMID 30850906›Full record

ReviewMikrochimica acta2019

Functionalized fluorescent carbon nanostructures for targeted imaging of cancer cells: a review.

Meghdad Pirsaheb, Somayeh Mohammadi, Abdollah Salimi, Mehrdad Payandeh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meghdad PirsahebResearch Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, 67198-51351, Iran.
Somayeh MohammadiResearch Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, 67198-51351, Iran. smhmohammadi4@gmail.com.ORCID 0000-0002-6405-4927
Abdollah SalimiDepartment of Chemistry, University of Kurdistan, Sanandaj, 66177-15175, Iran.
Mehrdad PayandehRegenerative Medicine Research Center, Kermanshah University of Medical Sciences, Kermanshah, 67148-69914, Iran.

Funding

Kermanshah University of Medical Sciences 96386
6 · The paper itself

Abstract

This short review (with 72 refs.) summarizes the state of the art in fluorometric methods for targeted imaging of cancer cells and tumor tissues in order to differentiate between normal cells and cancer cells. Following an introduction into the field and after presenting an overview on the most commonly used carbon dots and graphene quantum dots, we describe methods based on peptide based targeting, aptamer based targeting, antibody based targeting, and ligand-based targeting. A concluding section summarizes the current state and challenges, and discusses future perspectives. Graphical abstract An overview is given on the applications of carbon dots (CDs) in target-specific imaging and differentiation of cancerous cells from normal cells. Several classes of ligands (including aptamers, peptides, antibodies), especially small molecules (such as FA)) have been reported for functionalizing of CDs.

Indexed as

Amino Acid SequenceAnimalsCarbonCell Line, TumorFluorescent DyesHumansMicroscopy, ConfocalMicroscopy, FluorescenceNeoplasmsQuantum DotsCarbonFluorescent DyesCancer cellsCarbon based materialsCell imagingCovalent and non-covalent modificationFolate receptorsHeteroatom dopingPolymer passivation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.