Evidence map›Paper›PMID 30850688›Full record

ArticleScientific reports2019

Provisional Tic Disorder is not so transient.

Soyoung Kim, Deanna J Greene, Emily C Bihun, Jonathan M Koller, Jacqueline M Hampton, Haley Acevedo, Angela M Reiersen, Bradley L Schlaggar, Kevin J Black

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Tourette syndrome.Nature reviews. Disease primers · 2026
    Review
  3. Article
  4. The Prevalence of Tic Disorders in Poland: Regional and Sex Differences.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Chronic tic cough in adults: a case report.Frontiers in medicine · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Diagnostic Hierarchy of Tic Disorders in Real-World Clinical Practice.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2023
    Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Clinical precursors of tics: an EMTICS study.Journal of child psychology and psychiatry, and allied disciplines · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Soyoung KimDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.ORCID http://orcid.org/0000-0003-2983-604X
Deanna J GreeneDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Emily C BihunDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Jonathan M KollerDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.ORCID http://orcid.org/0000-0002-1409-5608
Jacqueline M HamptonDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, United States.
Haley AcevedoDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Angela M ReiersenDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Bradley L SchlaggarKennedy Krieger Institute, Baltimore, MD, United States.
Kevin J BlackDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States. kevin@wustl.edu.ORCID http://orcid.org/0000-0002-6921-9567
Washington University in St. Louis · USKennedy Krieger Institute · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
The New Tics Study: A Novel Approach to Pathophysiology and Cause of Tic DisordersR01MH104030 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2017 to 2021
$3.3M
Training New Investigators in Neuroimaging and in the Neuropsychiatry of MovementK24MH087913 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2010 to 2014
$818k
PREDICTING OUTCOME IN CHILDREN WITH TIC DISORDERS USING NEUROIMAGING DATAK01MH104592 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2014 to 2018
$723k
PREDICTING OUTCOME IN CHILDREN WITH NEW-ONSET TICS USING NEUROIMAGING DATAR21NS091635 · NINDS · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J, SCHLAGGAR, BRADLEY L · 2015 to 2016
$419k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCRR NIH HHS UL1 RR024992NICHD NIH HHS U54 HD087011NIMH NIH HHS K01 MH104592NIMH NIH HHS K24 MH087913NIMH NIH HHS R01 MH104030NINDS NIH HHS R21 NS091635
6 · The paper itself

Abstract

Motor and vocal tics are common in childhood. The received wisdom among clinicians is that for most children the tics are temporary, disappearing within a few months. However, that common clinical teaching is based largely on biased and incomplete data. The present study was designed to prospectively assess outcome of children with what the current nomenclature calls Provisional Tic Disorder. We identified 43 children with recent onset tics (mean 3.3 months since tic onset) and re-examined 39 of them on the 12-month anniversary of their first tic. Tic symptoms improved on a group level at the 12-month follow-up, and only two children had more than minimal impairment due to tics. Remarkably, however, tics were present in all children at follow-up, although in several cases tics were apparent only when the child was observed remotely by video. Our results suggest that remission of Provisional Tic Disorder is the exception rather than the rule. We also identified several clinical features present at the first examination that predict one-year outcome; these include baseline tic severity, subsyndromal autism spectrum symptoms, and the presence of an anxiety disorder.

Indexed as

BrainChildFemaleHumansMagnetic Resonance ImagingMaleNeuroimagingNeuropsychological TestsRemission, SpontaneousSeverity of Illness IndexTic DisordersTime FactorsTourette SyndromeVideo Recording

Identifiers

PMID30850688
PMCPMC6408476
OpenAlexW2920228938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.