ArticleScientific reports2019
Parasitoid envenomation alters the Galleria mellonella midgut microbiota and immunity, thereby promoting fungal infection.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Review
- Immune and Metabolic Responses inInsects · 2026Article
- Guava root exudate-driven rhizosphere microorganisms changes transmitted to foliar-feeding insects influence their feeding behaviour.Plant biotechnology journal · 2025Article
- Caterpillar-parasitoid interactions: species-specific influences on host microbiome composition.FEMS microbiology ecology · 2024Article
- Effect ofInsects · 2024Article
- Article
- Shaping the Microbial Landscape: Parasitoid-Driven Modifications of Bactrocera dorsalis Microbiota.Microbial ecology · 2024Article
- Article
- Effects of passages through an insect or a plant on virulence and physiological properties of the fungusPeerJ · 2023Article
- The immunostimulatory role of anFrontiers in insect science · 2023Article
- Associated bacteria of a pine sawyer beetle confer resistance to entomopathogenic fungi via fungal growth inhibition.Environmental microbiome · 2022Article
- Article
- The diarrhetic shellfish-poisoning toxin, okadaic acid, provokes gastropathy, dysbiosis and susceptibility to bacterial infection in a non-rodent bioassay, Galleria mellonella.Archives of toxicology · 2021Article
- A Neurotoxic Insecticide Promotes Fungal Infection in Aedes aegypti Larvae by Altering the Bacterial Community.Microbial ecology · 2021Article
- Fungus Metarhizium robertsii and neurotoxic insecticide affect gut immunity and microbiota in Colorado potato beetles.Scientific reports · 2021Article
- Article
- Parasitoid Causes Cascading Effects on Plant-Induced Defenses Mediated Through the Gut Bacteria of Host Caterpillars.Frontiers in microbiology · 2021Article
- Interplay between Fungal Infection and Bacterial Associates in the Wax MothJournal of fungi (Basel, Switzerland) · 2020Article
- The microbiome of the invertebrate model host Galleria mellonella is dominated by Enterococcus.Animal microbiome · 2019Article
- Combined effect of the entomopathogenic fungusPeerJ · 2019Article
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Authors and funding
11 authors.
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Abstract
Gut bacteria influence the development of different pathologies caused by bacteria, fungi and parasitoids in insects. Wax moth larvae became more susceptible to fungal infections after envenomation by the ectoparasitoid Habrobracon hebetor. In addition, spontaneous bacterioses occurred more often in envenomated larvae. We analyzed alterations in the midgut microbiota and immunity of the wax moth in response to H. hebetor envenomation and topical fungal infection (Beauveria bassiana) alone or in combination using 16S rRNA sequencing, an analysis of cultivable bacteria and a qPCR analysis of immunity- and stress-related genes. Envenomation led to a predominance shift from enterococci to enterobacteria, an increase in CFUs and the upregulation of AMPs in wax moth midguts. Furthermore, mycosis nonsignificantly increased the abundance of enterobacteria and the expression of AMPs in the midgut. Combined treatment led to a significant increase in the abundance of Serratia and a greater upregulation of gloverin. The oral administration of predominant bacteria (Enterococcus faecalis, Enterobacter sp. and Serratia marcescens) to wax moth larvae synergistically increased fungal susceptibility. Thus, the activation of midgut immunity might prevent the bacterial decomposition of envenomated larvae, thus permitting the development of fungal infections. Moreover, changes in the midgut bacterial community may promote fungal killing.
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