ArticleScientific reports2019
Cytotoxicity profiling of deep eutectic solvents to human skin cells.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Deep Eutectic Solvents for Ammonia Capture and Detection: Molecular Design, Absorption Mechanisms, and Analytical Applications: A Brief Review.International journal of molecular sciences · 2026Review
- Muscle-Conformal Injectable Eutectogel Platform With Activated Adhesion for Therapeutic Epidermal Bioelectronics.Advanced healthcare materials · 2026Article
- Beyond Composition: Structure-Activity Relationships in Bioactive Deep Eutectic Systems.Pharmaceutics · 2026Review
- Organic acid-based deep eutectic solvents (DESs) are potent antimicrobial agents against antibiotic-resistant bacteria and viruses.Current research in microbial sciences · 2026Article
- Article
- Tailorable Antibacterial Activity and Biofilm Eradication Properties of Biocompatible α-Hydroxy Acid-Based Deep Eutectic Solvents.Pharmaceutics · 2025Article
- Eutectogels: Recent Advances, Design Strategies, and Emerging Applications in Biotechnology.Gels (Basel, Switzerland) · 2025Review
- The Versatility of NADES Across Applications.Molecules (Basel, Switzerland) · 2025Review
- Volatile fatty acids recovery from thermophilic acidogenic fermentation using hydrophobic deep eutectic solvents.Journal of biological engineering · 2025Article
- Sustainable extraction of phytochemicals from Mentha arvensis using supramolecular eutectic solvent via microwave Irradiation: Unveiling insights with CatBoost-Driven feature analysis.Ultrasonics sonochemistry · 2025Article
- New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents.Molecules (Basel, Switzerland) · 2025Review
- Anti-inflammatory effects of cyclodextrin nanoparticles enable macrophage repolarization and reduce inflammation.Discover nano · 2024Article
- Electrocatalysis in deep eutectic solvents: from fundamental properties to applications.Chemical science · 2024Review
- Microspheres Based on Blends of Chitosan Derivatives with Carrageenan as Vitamin Carriers in Cosmeceuticals.Polymers · 2024Article
- Review
- Review
- Nature of a Tetrabutylammonium Chloride-Levulinic Acid Deep Eutectic Solvent.Industrial & engineering chemistry research · 2023Article
- Therapeutic Liquid Eutectic Solvents in Lipid Nanoparticles as Drug Vehicles-A Proof of Concept.International journal of molecular sciences · 2023Article
- Choline chloride-based deep eutectic solvent as an inhibitor of metalloproteases (collagenase and elastase) in cosmetic formulation.3 Biotech · 2023Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tailor-made character of deep eutectic solvents (DES) turns them very attractive to be used in several applications, including in health-related areas such as pharmaceutical, nutraceutical, and cosmetic industries. However, although DES has been touted as "green" solvents, several works proved that their potential toxicity should not be neglected. Using the premise of DES applicability in the cosmetic and pharmaceutical sectors, we chose two cell lines to work as a skin model (keratinocytes HaCaT and tumor melanocytes MNT-1), to assess DES cytotoxicity. The effect of three different hydrogen bond acceptors (HBA) ([Chol]Cl, [N
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.