Evidence map›Paper›PMID 30850627›Full record

ArticleScientific reports2019

RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones.

Antonio Pezone, Candida Zuchegna, Alfonso Tramontano, Antonella Romano, Giusi Russo, Mariarosaria de Rosa, Maria Vinciguerra, Antonio Porcellini, Max E Gottesman, Enrico Vittorio Avvedimento

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Role of eRNAs in Cardiovascular Diseases.Current cardiology reviews · 2026
    Review
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  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Inflammation and DNA damage: cause, effect or both.Nature reviews. Rheumatology · 2023
    Review
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Antonio PezoneDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
Candida ZuchegnaDipartimento di Biologia, Università di Napoli Federico II, Naples, Italy.ORCID 0000-0002-8494-8602
Alfonso TramontanoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
Antonella RomanoDipartimento di Biologia, Università di Napoli Federico II, Naples, Italy.
Giusi RussoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
Mariarosaria de RosaDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
Maria VinciguerraDNA Metabolism Laboratory, IFOM, The FIRC Institute of Molecular Oncology, Milan, Italy.
Antonio PorcelliniDipartimento di Biologia, Università di Napoli Federico II, Naples, Italy. antonio.porcellini@unina.it.
Max E GottesmanInstitute of Cancer Research, Columbia University Medical Center, New York, NY, 10032, USA. meg8@columbia.edu.
Enrico Vittorio AvvedimentoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy. avvedim@unina.it.
University of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITColumbia University Irving Medical Center · USIFOM · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We show that transcription induced by nuclear receptors for estrogen (E

Indexed as

Caspase 9Caveolin 1Cell Cycle ProteinsChromatinDNA-Binding ProteinsEnhancer Elements, GeneticEstradiolFemaleHumansMCF-7 CellsModels, BiologicalPromoter Regions, GeneticProto-Oncogene Proteins c-bcl-2Ribonuclease HRNARNA StabilityBCL2 protein, humanCASP9 protein, humanCaspase 9CAV1 protein, humanCaveolin 1Cell Cycle ProteinsChromatinDNA-Binding ProteinsEstradiolProto-Oncogene Proteins c-bcl-2RAD21 protein, humanRibonuclease Hribonuclease HIRNATretinoin

Identifiers

PMID30850627
PMCPMC6408484
OpenAlexW2918283811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.