Evidence map›Paper›PMID 30850428›Full record

ArticleApplied and environmental microbiology2019

The PlyB Endolysin of Bacteriophage vB_BanS_Bcp1 Exhibits Broad-Spectrum Bactericidal Activity against

Raymond Schuch, Adam J Pelzek, Daniel C Nelson, Vincent A Fischetti

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Review
  7. Lysins as a powerful alternative to combat Bacillus anthracis.Applied microbiology and biotechnology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
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  19. Article
  20. Phage therapy as a revolutionary medicine against Gram-positive bacterial infections.Beni-Suef University journal of basic and applied sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raymond SchuchLaboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York, USA.ORCID 0000-0003-4324-573X
Adam J PelzekLaboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York, USA.
Daniel C NelsonLaboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York, USA.ORCID 0000-0003-3248-4831
Vincent A FischettiLaboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York, USA vaf@rockefeller.edu.
Rockefeller University · US

Funding

Isolaton of new phage enzymes to kill B. anthracisR01AI057472 · NIAID · ROCKEFELLER UNIVERSITY · PI FISCHETTI, VINCENT A. · 2004 to 2014
$3.9M
NIAID NIH HHS R01 AI057472
6 · The paper itself

Abstract

Lytic bacteriophages (or phages) drive bacterial mortality by elaborating exquisite abilities to bind, breach, and destroy bacterial cell membranes and subjugate critical bacterial cell functions. These antimicrobial activities make phages ideal candidates to serve as, or provide sources of, biological control measures for bacterial pathogens. In this study, we isolated the

Indexed as

AnimalsAnti-Bacterial AgentsBacillus anthracisBacillus cereusBacillus PhagesEndopeptidasesFemaleMiceMice, Inbred BALB CMyoviridaeSoil MicrobiologyWaste Disposal FacilitiesAnti-Bacterial AgentsendolysinEndopeptidasesBacillus anthracisBacillus cereusbacteriophageendolysin

Identifiers

PMID30850428
PMCPMC6495760
OpenAlexW2919748751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.