Evidence map›Paper›PMID 30850013›Full record

ReviewCritical care (London, England)2019

Heterogeneity in sepsis: new biological evidence with clinical applications.

Aleksandra Leligdowicz, Michael A Matthay

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05591924 (Prospective Observational Study of Biology of Critical Illness), which is not on this map. Cited by 135 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05591924 recruitingnot on this mapstarted 2024, after this paper: background citation

Prospective Observational Study of Biology of Critical Illness

Typeobservational_patient_registrySponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2024 to 2034Enrolled1,000ConditionsSepsis, ARDS, Critical Illness, Neurocognitive DysfunctionArmsPhelebotomy, Broncheoalveolar Lavage, Tracheal Aspirate, Rectal Swab
3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Observational
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  20. Review

75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aleksandra LeligdowiczCardiovascular Research Institute, University of California-San Francisco, San Francisco, CA, USA. aleksandra.leligdowicz@uhn.ca.
Michael A MatthayCardiovascular Research Institute, University of California-San Francisco, San Francisco, CA, USA.

Funding

NOVEL PARACRINE MECHANISMS FOR CELL-BASED THERAPY OF INJURED LUNGSR01HL134828 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI JI, HONG-LONG · 2017 to 2025
$3.4M
NHLBI NIH HHS R01 HL134828
6 · The paper itself

Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2019. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2019 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901 .

Indexed as

Critical CareHumansIntensive Care UnitsSepsis

Identifiers

PMID30850013
PMCPMC6408778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.