ReviewBMC pediatrics2019
Is vitamin C enough? A case report of scurvy in a five-year-old girl and review of the literature.
Review in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- A comprehensive review on the co-occurrence of scurvy and anorexia nervosa.Frontiers in nutrition · 2024Pooled it
- Effect of an educational program on mothers' reported practice regarding care of their children with vitamin deficiencies.BMC nutrition · 2026Article
- Scurvy, a not obsolete disorder: Clinical report in eight young children and literature review.Open medicine (Warsaw, Poland) · 2025Review
- The Impact of Vitamin Deficiencies on Oral Manifestations in Children.Dentistry journal · 2024Review
- Unusual Presentation of Pediatric Scurvy: A Necrotic Gastrostomy Tube Site in a 14-Year-Old Boy.The American journal of case reports · 2023Article
- Selenium deficiency and scurvy due to an imbalanced diet of snacks and lacto-fermenting drinks: a case report of a 7-year-old boy with autism spectrum disorder.BMC nutrition · 2023Article
- Carbon Nanotube and Its Derived Nanomaterials Based High Performance Biosensing Platform.Biosensors · 2022Review
- Article
- A Narrative Review on Pediatric Scurvy: The Last Twenty Years.Nutrients · 2022Review
- When the limp has a dietary cause: A retrospective study on scurvy in a tertiary Italian pediatric hospital.Frontiers in pediatrics · 2022Article
- Scurvy mimicking as systemic lupus erythematosus.BMJ case reports · 2021Article
- Vitamin C deficiency and impact of vitamin C administration among pediatric patients with advanced chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Pediatric Scurvy: How an Old Disease Is Becoming a New Problem.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2020Article
- Scurvy: A New Old Cause of Skeletal Pain in Young Children.Frontiers in pediatrics · 2020Article
- Scurvy: A Rare Cause of Anemia.Cureus · 2019Article
- Correction to: Is vitamin C enough? A case report of scurvy in a five-year-old girl and review of the literature.BMC pediatrics · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNumerous cases of scurvy secondary to diet limitations have been reported in the literature with most being boys with special needs. To date, the focus of the literature describing vitamin C deficiency has been the medical sequelae of the deficiency. There has been little attention given underlying diet limitations causing the vitamin C deficiency. CASE PRESENTATION: A five-year-old female with typical development initially presented with rash, then later for pain in both lower extremities. After evaluation revealed vitamin C deficiency, she was admitted into an intensive day treatment feeding program. A feeding assessment found she had life-long problems with eating and had a diet that never exceeded ten foods. Across the course of treatment, she learned to eat 29 new foods. At six-month follow-up her body mass index had increased from the 1st to the 61st percentile. At one-year follow-up her body mass index was at the 85th percentile. All sequalae of her deficiency resolved.
conclusionsThis case is unusual as most reported studies describe males with special needs. The severity of her eating issues suggest providers may consider referral to allied health professionals to address diet limitations for both children identified with nutrient deficiencies as well as children whose selective eating places them at risk for nutritional deficiencies or problems with growth. The child we described was anemic, like 42% of children described in the case literature on scurvy and like 32% of the children in this literature, our patient was underweight. In the literature, comorbid nutrient deficiencies were reported in 22% of the scurvy case studies. We suggest vitamin C supplementation is a necessary component for addressing vitamin C deficiency, but insufficient for addressing the diet limitations causing the nutrient deficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.