Evidence map›Paper›PMID 30849699›Full record

ReviewCurrent opinion in biotechnology2019

Exploiting BBB disruption for the delivery of nanocarriers to the diseased CNS.

Benjamin J Umlauf, Eric V Shusta

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Review
  3. Lipid and polymeric nanocarriers for siRNA delivery to the brain.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Review
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  5. Article
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  8. Extracellular Vesicles as a Potential Therapy for Stroke.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Benjamin J UmlaufDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, United States.
Eric V ShustaDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, United States. Electronic address: eshusta@wisc.edu.
University of Wisconsin–Madison · US

Funding

Identification of Lamprey Antibodies Capable of Noninvasive Brain Drug DeliveryR01NS099158 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI SHUSTA, ERIC V · 2017 to 2021
$1.7M
NINDS NIH HHS R01 NS099158
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood-Brain BarrierDrug Delivery Systems

Identifiers

PMID30849699
PMCPMC6728237
OpenAlexW2947476618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.