Evidence map›Paper›PMID 30849588›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2019

Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (Oncorhynchus mykiss).

Daniel Bussolaro, Stephanie L Wright, Sabine Schnell, Kristin Schirmer, Nicolas R Bury, Volker M Arlt

Open access · hybridAbstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Daniel BussolaroDepartment of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, Franklin-Wilkins Building, London, SE1 9NH, United Kingdom; Federal Institute of Education, Science and Technology of Paraná, Curitiba Campus, CEP: 80.230 - 150., Curitiba, PR, Brazil.
Stephanie L WrightDepartment of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, Franklin-Wilkins Building, London, SE1 9NH, United Kingdom.
Sabine SchnellDepartment of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, Franklin-Wilkins Building, London, SE1 9NH, United Kingdom.
Kristin SchirmerDepartment of Environmental Toxicology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Überlandstrasse 133, 8600, Dübendorf, Switzerland.
Nicolas R BurySchool of Science, Technology and Engineering, University of Suffolk, James Hehir Building, Neptune Quay, Ipswich, IP4 1QJ, Suffolk, United Kingdom. Electronic address: n.bury@uos.ac.uk.
Volker M ArltDepartment of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, Franklin-Wilkins Building, London, SE1 9NH, United Kingdom; NIHR Health Protection Research Unit in Health Impact of Environmental Hazards, King's College London in partnership with Public Health England and Imperial College London, Franklin-Wilkins Building, London, SE1 9NH, United Kingdom.
King's College London · GBSwiss Federal Institute of Aquatic Science and Technology · CHUniversity of Suffolk · GB

Funding

Cancer Research UK A14329Cancer Research UK A3352Wellcome Trust 101126
6 · The paper itself

Abstract

Microscopic plastic (MP) particles are a ubiquitous contaminant in aquatic environments, which may bind hydrophobic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), altering their environmental fate and interactions with biota. Using rainbow trout gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells we investigated the effects of polystyrene microbeads (PS-MBs; 220 nm) on the cyto- and genotoxicity of the environmental pollutants benzo[a]pyrene (BaP) and 3-nitrobenzanthrone (3-NBA) over 48 h (0, 0.1, 1 and 10 μM). The Alamar Blue bioassay, used to assess cytotoxicity, showed that both pollutants significantly decreased cell viability by 10-20% at 10 μM in both cell lines after 48 h whereas PS-MBs (5 or 50 μg mL

Indexed as

AnimalsCell LineComet AssayDNA DamageDrug SynergismEpithelial CellsGillsIntestinesOncorhynchus mykissPolycyclic Aromatic HydrocarbonsWater Pollutants, ChemicalPolycyclic Aromatic HydrocarbonsWater Pollutants, ChemicalFish cell linesGenotoxicityMicroplastic beadsPolycyclic aromatic hydrocarbonsRTgill-W1RTgutGC

Identifiers

PMID30849588
PMCPMC6794159
OpenAlexW2916351395

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.