Evidence map›Paper›PMID 30849376›Full record

ArticleCell2019

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming.

Geoffrey Schiebinger, Jian Shu, Marcin Tabaka, Brian Cleary, Vidya Subramanian, Aryeh Solomon, Joshua Gould, Siyan Liu, Stacie Lin, Peter Berube and 8 more

Abstract readPublished Erratum
In one paragraph

Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

  1. Article
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  12. Single cell RNA sequencing shows that cells expressing Sox9 postnatally populate most skeletal lineages in mouse bone.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Geoffrey Schiebinger
Jian Shu
Marcin Tabaka
Brian Cleary
Vidya Subramanian
Aryeh Solomon
Joshua Gould
Siyan Liu
Stacie Lin
Peter Berube
Lia Lee
Jenny Chen
Justin Brumbaugh
Philippe Rigollet
Konrad Hochedlinger
Rudolf Jaenisch
Aviv Regev
Eric S Lander

Funding

Tool and Technology Development CoreU19MH114821 · NIMH · COLD SPRING HARBOR LABORATORY · PI HUANG, Z JOSH · 2017 to 2021
$64.5M
In situ transcriptional analysis of brain circuits at single cell resolutionR01MH111502 · NIMH · HARVARD UNIVERSITY · PI DULAC, CATHERINE, REGEV, AVIV · 2016 to 2018
$4.6M
Graduate Training in Computational and Systems BiologyT32GM087237 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BURGE, CHRISTOPHER B · 2009 to 2023
$4.6M
An integrated multiplexed genomic assay for low input clinical samples1U24AI118672 · NIAID · BROAD INSTITUTE, INC. · PI SHALEK, ALEX K · 2015 to 2019
$2.0M
NIAID NIH HHS U24 AI118672NIGMS NIH HHS T32 GM087237NIMH NIH HHS R01 MH111502NIMH NIH HHS U19 MH114821
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID30849376
PMCPMC6615720

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.