Evidence map›Paper›PMID 30849369›Full record

ArticleCell2019

Some Like it HOT: Horizontal Operon Transfer.

Amelia R I Lindsey, Irene L G Newton

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amelia R I LindseyDepartment of Biology, Indiana University, Bloomington, IN 47405, USA.
Irene L G NewtonDepartment of Biology, Indiana University, Bloomington, IN 47405, USA. Electronic address: irnewton@indiana.edu.
Indiana University Bloomington · US

Funding

Type IV Secretion in an Obligate SymbiontR21AI137918 · NIAID · TRUSTEES OF INDIANA UNIVERSITY · PI NEWTON, IRENE · 2018 to 2019
$443k
Determining the mechanism of Wolbachia pathogen blockingR21AI121849 · NIAID · TRUSTEES OF INDIANA UNIVERSITY · PI NEWTON, IRENE · 2017 to 2018
$420k
NIAID NIH HHS R21 AI121849NIAID NIH HHS R21 AI137918
6 · The paper itself

Abstract

While horizontal gene transfer (HGT) is well documented in bacteria, the role and frequency of HGT across eukaryotes remains poorly understood. Kominek et al. identified a horizontal operon transfer (HOT) event, with clear evidence for selection to facilitate gene expression, that has allowed a group of yeasts to scavenge iron using bacterially derived genes.

Indexed as

EukaryotaBacteriaEukaryotic CellsGene Transfer, HorizontalOperon

Identifiers

PMID30849369
OpenAlexW2920740532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.