Trial reportClinical transplantation2019
Infections after kidney transplantation. Does age matter?
Trial report in Clinical transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Incidence of Cytomegalovirus (CMV) Infection in After Kidney Transplant Patients: A Systematic Review and Meta-Analysis.Reviews in medical virology · 2026Pooled it
- Favorable Adherence and Tolerability of Letermovir Versus Valganciclovir for Cytomegalovirus Prophylaxis in Kidney Transplant Recipients Aged 65 y or Older: Findings From a Randomized, Phase 3 Trial.Transplantation direct · 2026Article
- Alemtuzumab Induction in Septuagenarians Undergoing Deceased Donor Kidney Transplantation.Clinical transplantation · 2026Article
- Long-Term Clinical Outcomes of ABO-Incompatible Kidney Transplantation in Patients With High Baseline Anti-A/B Antibody Titers.Journal of Korean medical science · 2025Article
- Necessity of induction agent modification for old age kidney transplant recipients.Kidney research and clinical practice · 2025Article
- Infection Risk in Older Kidney Transplant Recipients: An Analysis in the Era of Expanded Age Limits.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Older Kidney Transplant Patients Are Over Immunosuppressed Using Standard Protocols With Differential Sex-Based Complications.Journal of transplantation · 2025Article
- Age-Related Risk After Kidney Transplantation: A Comprehensive Analysis of Infection Burden, Graft Outcomes, and Mortality.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Age-modified risk factors for mortality of non-elderly adult kidney transplant recipients: a retrospective database analysis.International urology and nephrology · 2024Article
- Evaluation of a Ureteral Stent Removal Protocol in Adult Kidney Transplant Recipients.Open forum infectious diseases · 2024Article
- Stratification of Kidney Transplant Recipients Into Five Subgroups Based on Temporal Disease Trajectories.Transplantation direct · 2024Article
- Infections in the first year of living related kidney transplantation in a young transplant cohort.BMC nephrology · 2023Observational
- UV-Assisted Hyperbranched Poly(β-amino ester) Modification of a Silica Membrane for Two-Step Microfluidic DNA Extraction from Blood.ACS applied materials & interfaces · 2023Article
- Impact of a Dedicated Pretransplant Infectious Disease Consultation on Respiratory Tract Infections in Kidney Allograft Recipients: A Retrospective Study of 516 Recipients.Pathogens (Basel, Switzerland) · 2023Article
- Kidney Transplant-Associated Viral Infection Rates and Outcomes in a Single-Centre Cohort.Viruses · 2022Article
- Prevalence of frailty and cognitive impairment in older transplant candidates - a preview to the Kidney Transplantation in Older People (KTOP): impact of frailty on outcomes study.BMC nephrology · 2022Observational
- The Prevalence of Neurological Complication after Renal Transplantation.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Chronic Kidney Allograft Disease: New Concepts and Opportunities.Frontiers in medicine · 2021Review
- The first report of kidney transplantation in a human immunodeficiency virus-positive recipient in Thailand and literature review: Encouragement for developing countries in Southeast Asia.SAGE open medical case reports · 2021Article
- Epidemiology, risk factors, and clinical impact of early post-transplant infection in older kidney transplant recipients: the Korean organ transplantation registry study.BMC geriatrics · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Infections threaten successful outcomes after kidney transplantation. Our aim was to determine if the number, types of infections and the risk factors for common infections differed between older compared to younger kidney transplant (KT) recipients in the first year after surgery. We performed a single-center retrospective cohort study. Between 2011 and 2015, 91 KTs were performed in patients ≥65 years of age; these were matched 1:1 (by year of transplantation, sex and race) to controls aged 40-60 years. Over 90% of both groups had an infectious complication. Urinary tract infections (UTIs) and cytomegalovirus (CMV) viremia were significantly more frequent in older recipients. Older adults had more late onset UTIs, including after stent removal. CMV viremia was more frequent in older adults in the 1-6 months post-transplant period. Due to our center-specific protocol utilizing pre-emptive monitoring in the CMV recipient-seropositive population, the higher CMV incidence in the aged recipient was driven by this subpopulation of older adults. No difference in pneumonias or bloodstream infections were found, nor in surgical complications, rejection or graft loss. Mortality was higher at 1-year post-transplant in the older recipients (9.9% vs 1.1%; P = 0.018). Prophylactic and immunosuppressive strategies may need to be altered for older KT recipients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.