Evidence map›Paper›PMID 30849124›Full record

SynthesisPLoS neglected tropical diseases2019

A systematic review of scabies transmission models and data to evaluate the cost-effectiveness of scabies interventions.

Naomi van der Linden, Kees van Gool, Karen Gardner, Helen Dickinson, Jason Agostino, David G Regan, Michelle Dowden, Rosalie Viney

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Mass Drug Administration for the Control of Scabies: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Pooled it
  2. Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
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  12. Review
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  18. Laboratory-based diagnosis of scabies: a review of the current status.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Review
  19. Scabies outbreak during COVID-19: an Italian experience.International journal of dermatology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Naomi van der LindenCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.ORCID 0000-0003-1646-9834
Kees van GoolCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.
Karen GardnerPublic Service Research Group, School of Business UNSW Canberra, Canberra, Australia.
Helen DickinsonPublic Service Research Group, School of Business UNSW Canberra, Canberra, Australia.
Jason AgostinoAcademic Unit of General Practice, Australian National University, Canberra, Australia.
David G ReganThe Kirby Institute, UNSW Sydney, Sydney, Australia.
Michelle DowdenOne Disease, Darwin, Australia.
Rosalie VineyCentre for Health Economics Research and Evaluation, University of Technology Sydney, Sydney, Australia.
University of Technology Sydney · AUUniversity of Canberra · AUAustralian National University · AUCharles Darwin University · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScabies is a common dermatological condition, affecting more than 130 million people at any time. To evaluate and/or predict the effectiveness and cost-effectiveness of scabies interventions, disease transmission modelling can be used.

objectiveTo review published scabies models and data to inform the design of a comprehensive scabies transmission modelling framework to evaluate the cost-effectiveness of scabies interventions.

methodsSystematic literature search in PubMed, Medline, Embase, CINAHL, and the Cochrane Library identified scabies studies published since the year 2000. Selected papers included modelling studies and studies on the life cycle of scabies mites, patient quality of life and resource use. Reference lists of reviews were used to identify any papers missed through the search strategy. Strengths and limitations of identified scabies models were evaluated and used to design a modelling framework. Potential model inputs were identified and discussed.

findingsFour scabies models were published: a Markov decision tree, two compartmental models, and an agent-based, network-dependent Monte Carlo model. None of the models specifically addressed crusted scabies, which is associated with high morbidity, mortality, and increased transmission. There is a lack of reliable, comprehensive information about scabies biology and the impact this disease has on patients and society. DISCUSSION: Clinicians and health economists working in the field of scabies are encouraged to use the current review to inform disease transmission modelling and economic evaluations on interventions against scabies.

Indexed as

Cost-Benefit AnalysisAnimalsAntiparasitic AgentsDecision TreesHumansIvermectinLife Cycle StagesMonte Carlo MethodQuality-Adjusted Life YearsSarcoptes scabieiScabiesAntiparasitic AgentsIvermectin

Identifiers

PMID30849124
PMCPMC6426261
OpenAlexW2922308746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.