Evidence map›Paper›PMID 30848964›Full record

ArticleBrain injury2019

MRS and DTI evidence of progressive posterior cingulate cortex and corpus callosum injury in the hyper-acute phase after Traumatic Brain Injury.

Tim P Lawrence, Adam Steel, Martyn Ezra, Mhairi Speirs, Pieter M Pretorius, Gwenaelle Douaud, Stamatios Sotiropoulos, Tom Cadoux-Hudson, Uzay E Emir, Natalie L Voets

Abstract read
In one paragraph

Article in Brain injury, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tim P Lawrencea FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.
Adam Steela FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.
Martyn Ezraa FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.
Mhairi Speirsb Department of Neuroscience , Oxford University Hospitals NHS Foundation Trust , Oxford , United Kingdom.
Pieter M Pretoriusb Department of Neuroscience , Oxford University Hospitals NHS Foundation Trust , Oxford , United Kingdom.
Gwenaelle Douauda FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.
Stamatios Sotiropoulosa FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.
Tom Cadoux-Hudsonb Department of Neuroscience , Oxford University Hospitals NHS Foundation Trust , Oxford , United Kingdom.
Uzay E Emira FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.
Natalie L Voetsa FMRIB Centre, Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , United Kingdom.

Funding

Medical Research Council MR/K006673/1Wellcome TrustWellcome Trust 203139/Z/16/Z
6 · The paper itself

Abstract

The posterior cingulate cortex (PCC) and corpus callosum (CC) are susceptible to trauma, but injury often evades detection. PCC Metabolic disruption may predict CC white matter tract injury and the secondary cascade responsible for progression. While the time frame for the secondary cascade remains unclear in humans, the first 24 h (hyper-acute phase) are crucial for life-saving interventions.

Indexed as

AdultAgedAged, 80 and overBrain Injuries, TraumaticCorpus CallosumDiffusion Tensor ImagingFemaleGray MatterGyrus CinguliHumansImage Processing, Computer-AssistedMagnetic Resonance SpectroscopyMaleMiddle AgedNeuroimagingWhite Mattercorpus callosumdiffuse axonal injuryMagnetic resonance imagingposterior cingulate cortexsecondary injury cascade

Identifiers

PMID30848964
PMCPMC6619394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.