ArticleLiver international : official journal of the International Association for the Study of the Liver2019
The relationship between coronary artery disease and cardiovascular events early after liver transplantation.
Article in Liver international : official journal of the International Association for the Study of the Liver, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- Impact of Preoperative Cardiac Screening Modality on Cardiovascular Outcomes After Liver Transplantation.Clinical transplantation · 2026Article
- Outcomes in Asymptomatic Patients Undergoing Coronary Revascularization Before Liver Transplantation.Journal of clinical medicine · 2025Article
- Risk factors associated with adverse cardiovascular events during orthotopic liver transplantation and the early post-transplant period.Croatian medical journal · 2025Article
- Safety, efficacy, and outcomes of invasive coronary angiography in liver transplant candidates.JHEP reports : innovation in hepatology · 2025Article
- Diagnostic accuracy and cost-effectiveness of the CAR-OLT score in predicting cardiac risk for liver transplantation.World journal of transplantation · 2025Article
- Heart transplantation: comparing the impact of modified heart preservation with conventional methods.Scientific reports · 2025Article
- Successful Percutaneous Coronary Stenting in End-Stage Liver Disease Patients Awaiting Liver Transplantation.Cureus · 2024Article
- Burden of Portal Hypertension Complications Is Greater in Liver Transplant Wait-Listed Registrants with End-Stage Liver Disease and Type 2 Diabetes.Digestive diseases and sciences · 2024Article
- Short- and Long-Term Outcomes of Patients with Postoperative Arrhythmia after Liver Surgery.Biomedicines · 2024Article
- Five-year all-cause mortality in critically ill liver transplant patients with coronary artery disease: analysis of acute-on chronic liver failure.Anesthesia and pain medicine · 2022Article
- Temporary postoperative myocardial injury and long-term survival in liver transplant patients with coronary artery disease.Anesthesia and pain medicine · 2022Article
- Excess Risk of Major Adverse Cardiovascular and Kidney Events after Acute Kidney Injury following Living Donor Liver Transplantation.Journal of clinical medicine · 2022Article
- Cardiac Risk Assessment in Liver Transplant Candidates: Current Controversies and Future Directions.Hepatology (Baltimore, Md.) · 2021Review
- Cardiac and Pulmonary Vascular Risk Stratification in Liver Transplantation.Clinics in liver disease · 2021Review
- PRO: Cardiac Catheterization Is the Optimal Strategy for Cardiovascular Risk Stratification in This Patient.Clinical liver disease · 2021Review
- Assessment of Malnutrition, Sarcopenia and Frailty in Patients with Cirrhosis: Which Tools Should We Use in Clinical Practice?Nutrients · 2020Review
- Pathogenesis of non-alcoholic fatty liver disease and implications on cardiovascular outcomes in liver transplantation.Translational gastroenterology and hepatology · 2020Review
- Indian National Association for the Study of Liver (INASL) Guidance Statements for Determining Futility in Liver Transplantation.Journal of clinical and experimental hepatologyReview
- Pre-Liver Transplant Cardiac Evaluation-Demystifying the Heart Under Stress or Unclogging the Coronaries?Journal of clinical and experimental hepatologyArticle
- Liver Transplantation: Contraindication and Ineligibility.Journal of clinical and experimental hepatologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND &
aimsCardiovascular complications are major contributors to mortality at liver transplantation (LT). However, the impact of coronary artery disease (CAD) on these complications is not well-understood as the literature is limited by non-invasive assessment of CAD, which is suboptimal in patients with cirrhosis. Thus, the current study evaluated cardiovascular events at LT stratified according to the presence and severity of CAD quantified on coronary angiography.
methodsAll patients who had LT from January 2010 to January 2017 were evaluated (N = 348), but analysis was restricted to patients who had coronary angiography prior to LT (N = 283). Protocol coronary angiography was performed in all patients' ages >50 years, history of CAD, abnormal cardiac stress test or risk factors for CAD. The primary outcome was a cardiovascular composite outcome including myocardial infraction (MI), cardiac arrest, stroke, cardiac death, heart failure or arrhythmia occurring within 4 weeks after LT.
resultsCAD was present in 92(32.5%) patients and 32(11.3%) had obstructive CAD. During the study period, 72(25.4%) patients met the primary cardiovascular outcome, the most common being arrhythmia (N = 59 or 20.8%). Non-ST elevation MI occurred in 11(3.9%) of patients. A total of 10 deaths (3.5%) occurred, of which 6(2.1%) were attributable to cardiac death. There was no evidence of a relationship between the presence and severity of CAD and composite cardiovascular events. In multiple regression modelling, only diabetes [OR 2.62, 95%CI (1.49, 4.64), P < 0.001] was associated with the likelihood of having a cardiovascular event.
conclusionCardiovascular disease mortality is the most important contributor of early mortality after LT but is not related to the severity of CAD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.