Evidence map›Paper›PMID 30848811›Full record

ArticleJAMA network open2019

Prevalence of Hypertension, Treatment, and Blood Pressure Targets in Canada Associated With the 2017 American College of Cardiology and American Heart Association Blood Pressure Guidelines.

Stephanie Garies, Sylvia Hao, Kerry McBrien, Tyler Williamson, Mingkai Peng, Nadia A Khan, Raj S Padwal, Hude Quan, Alexander A Leung, for Hypertension Canada’s Research and Evaluation Committee

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pharmacotherapy for mild hypertension.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Is lowering the threshold for blood pressure diagnosis worth it?Canadian family physician Medecin de famille canadien · 2026
    Article
  5. Review
  6. Article
  7. Article
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  15. Article
  16. Potential benefits and harms of various arterial hypertension guidelines.International Journal of Cardiology. Hypertension · 2020
    Article
  17. Observational
  18. Article
  19. Hypertension prevalence in Colombian Patients Evaluated with Ambulatory Blood Pressure Monitoring According to Changes in Clinical Guidelines Between 2017-2018.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Stephanie GariesDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Sylvia HaoDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Kerry McBrienDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Tyler WilliamsonDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Mingkai PengDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Nadia A KhanDivision of General Internal Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Raj S PadwalDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Hude QuanDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Alexander A LeungDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
for Hypertension Canada’s Research and Evaluation Committee
University of Calgary · CACentre for Advancing Health Outcomes · CAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: The 2017 American College of Cardiology and American Heart Association (ACC/AHA) blood pressure (BP) guidelines redefined hypertension using a BP threshold of 130/80 mm Hg or greater and applied a treatment target of less than 130/80 mm Hg. Objective: To evaluate the potential change in the diagnosis, treatment, and control of hypertension in a Canadian cohort of patients with hypertension attending primary care practices using the ACC/AHA guidelines. Design, Setting, and Participants: This cross-sectional study used primary care practices across Canada electronic medical record data from the Canadian Primary Care Sentinel Surveillance Network, extracted as of June 30, 2015. Adults with at least 1 primary care encounter in the previous 2 years (July 1, 2013, to June 30, 2015) were included in the study. Those with current hypertension were identified using a validated definition consisting of diagnoses, billing codes, and/or antihypertensive medication from within the primary care electronic medical record. Data analysis was conducted from December 2017 to July 2018. Main Outcomes and Measures: Proportion of individuals with a diagnosis of hypertension, prescribed antihypertensive medication, and meeting treatment BP targets. Results: Of the 594 492 Canadian participants included in the study, 144 348 (24.2%) had hypertension (45.6% male; mean [SD] age, 65.5 [14.5] years). On applying the ACC/AHA guidelines, 252 279 individuals (42.4%) were considered hypertensive and half (51.0%; 95% CI, 50.8%-51.2%) were prescribed an antihypertensive medication. Individuals who were not previously considered to have hypertension but were reclassified as having elevated BP using the lower cutoff of 130/80 mm Hg or greater tended to be younger and were at lower cardiovascular risk. There was a shift toward more individuals requiring antihypertensive treatment, particularly in the lower-risk categories. The crude prevalence of hypertension increased from 13.3% to 32.0% in those aged 18 to 64 years, and of those aged 65 years and older, 16.6% more individuals were reclassified as having hypertension (from 55.2% to 71.8%). Only 12.3% of those who were considered at high risk were reclassified as hypertensive. Conclusions and Relevance: Adoption of the ACC/AHA BP guidelines would result in a near doubling in the prevalence of hypertension in Canada. The changes would largely affect individuals who are younger and at low to moderate cardiovascular risk.

Indexed as

Blood Pressure DeterminationHypertensionPrimary Health CareAgedAntihypertensive AgentsCanadaCohort StudiesCross-Sectional StudiesFemaleHealth Care SurveysHumansMaleMiddle AgedPractice Guidelines as TopicPrevalenceRisk FactorsAntihypertensive Agents

Identifiers

PMID30848811
PMCPMC6484648
OpenAlexW2922508578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.