Evidence map›Paper›PMID 30848345›Full record

ArticleCurrent genetics2019

Botcinic acid biosynthesis in Botrytis cinerea relies on a subtelomeric gene cluster surrounded by relics of transposons and is regulated by the Zn

Antoine Porquier, Javier Moraga, Guillaume Morgant, Bérengère Dalmais, Adeline Simon, Hind Sghyer, Isidro G Collado, Muriel Viaud

Abstract read
PubMed Publisher
In one paragraph

Article in Current genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  6. Article
  7. Revealing Hidden Genes inInternational journal of molecular sciences · 2024
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  8. Genome Comparisons betweenJournal of fungi (Basel, Switzerland) · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Genome-Wide Characterization of Light-Regulated Gene Expression inInternational journal of molecular sciences · 2023
    Article
  13. From Genes to Molecules, Secondary Metabolism inPlants (Basel, Switzerland) · 2023
    Review
  14. TheJournal of fungi (Basel, Switzerland) · 2023
    Article
  15. Biology · 2022
    Article
  16. Induction of Diverse Cryptic Fungal Metabolites by Steroids and Channel Blockers.Angewandte Chemie (International ed. in English) · 2022
    Article
  17. Article
  18. The NecrotrophFrontiers in plant science · 2022
    Article
  19. Article
  20. Genetic Diversity ofFrontiers in plant science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Antoine PorquierUMR BIOGER, INRA, AgroParisTech, Université Paris-Saclay, 78850, Thiverval-Grignon, France.ORCID http://orcid.org/0000-0003-3088-5447
Javier MoragaDepartamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, 11510, Puerto Real, Cádiz, Spain.ORCID http://orcid.org/0000-0001-6383-924X
Guillaume MorgantUMR BIOGER, INRA, AgroParisTech, Université Paris-Saclay, 78850, Thiverval-Grignon, France.
Bérengère DalmaisUMR BIOGER, INRA, AgroParisTech, Université Paris-Saclay, 78850, Thiverval-Grignon, France.
Adeline SimonUMR BIOGER, INRA, AgroParisTech, Université Paris-Saclay, 78850, Thiverval-Grignon, France.
Hind SghyerUMR BIOGER, INRA, AgroParisTech, Université Paris-Saclay, 78850, Thiverval-Grignon, France.
Isidro G ColladoDepartamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, 11510, Puerto Real, Cádiz, Spain.ORCID http://orcid.org/0000-0002-8612-0593
Muriel ViaudUMR BIOGER, INRA, AgroParisTech, Université Paris-Saclay, 78850, Thiverval-Grignon, France. viaud@versailles.inra.fr.ORCID http://orcid.org/0000-0001-8341-0555
AgroParisTech · FRUniversidad de Cádiz · ESUniversité Paris-Sud · FR

Funding

mineco-feder AGL2015-65684-C2-1-R
6 · The paper itself

Abstract

Botcinic acid is a phytotoxic polyketide involved in the virulence of the gray mold fungus Botrytis cinerea. Here, we aimed to investigate the specific regulation of the cluster of Bcboa genes that is responsible for its biosynthesis. Our analysis showed that this cluster is located in a subtelomeric genomic region containing alternating G + C/A + T-balanced regions, and A + T-rich regions made from transposable elements that underwent RIP (Repeat-Induced Point mutation). Genetic analyses demonstrated that BcBoa13, a putative Zn

Indexed as

BotrytisDNA Transposable ElementsGene Expression Regulation, FungalMultigene FamilyPlant DiseasesPoint MutationPolyketidesTranscription FactorsZincbotcinic acidDNA Transposable ElementsPolyketidesTranscription FactorsZincBotcinic acidBotrytis cinereaRepeat-induced point mutationSecondary metabolismToxinZn2Cys6 transcription factor

Identifiers

PMID30848345
OpenAlexW2921224140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.