Evidence map›Paper›PMID 30848237›Full record

ReviewMicrobiology spectrum2019

Type I Secretion Systems-One Mechanism for All?

Olivia Spitz, Isabelle N Erenburg, Tobias Beer, Kerstin Kanonenberg, I Barry Holland, Lutz Schmitt

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Traits analysis of an aphid-killingFrontiers in insect science · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Comparative genomics of 'Microbial genomics · 2025
    Article
  15. Article
  16. A catalog of proteins released fromMicrobiology spectrum · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Genotypes and associated traits inFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Olivia SpitzInstitute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Isabelle N ErenburgInstitute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Tobias BeerInstitute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Kerstin KanonenbergInstitute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
I Barry HollandInstitute of Genetics and Microbiology, University of Paris-Sud, Orsay, France.
Lutz SchmittInstitute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Heinrich Heine University Düsseldorf · DEUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type I secretion systems (T1SS) are widespread in Gram-negative bacteria, especially in pathogenic bacteria, and they secrete adhesins, iron-scavenger proteins, lipases, proteases, or pore-forming toxins in the unfolded state in one step across two membranes without any periplasmic intermediate into the extracellular space. The substrates of T1SS are in general characterized by a C-terminal secretion sequence and nonapeptide repeats, so-called GG repeats, located N terminal to the secretion sequence. These GG repeats bind Ca

Indexed as

Bacterial ProteinsBacterial Secretion SystemsBiological TransportGram-Negative BacteriaProtein TransportType I Secretion SystemsBacterial ProteinsBacterial Secretion SystemsType I Secretion Systems

Identifiers

PMID30848237
PMCPMC11588160
OpenAlexW2921806522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.