Evidence map›Paper›PMID 30848083›Full record

SynthesisJournal of clinical hypertension (Greenwich, Conn.)2019

The burden of hypertensive disorders of pregnancy in Africa: A systematic review and meta-analysis.

Jean Jacques Noubiap, Jean Joel Bigna, Ulrich Flore Nyaga, Ahmadou M Jingi, Arnaud D Kaze, Jobert Richie Nansseu, Joël Fokom Domgue

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Characteristics of longitudinal maternal health studies in sub-Saharan Africa: A systematic mapping of literature between 2012 and 2022.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Article
  13. Article
  14. Low-dose aspirin and anaemia risk in pregnancy: A scoping review with emphasis on low- and middle-income contexts.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
    Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jean Jacques NoubiapDepartment of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-7722-9757
Jean Joel BignaFaculty of Medicine, University of Paris Sud XI, Le Kremlin-Bicêtre, France.ORCID 0000-0001-8018-6279
Ulrich Flore NyagaDepartment of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Ahmadou M JingiDepartment of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Arnaud D KazeUniversity of Maryland Medical Center Midtown Campus, Baltimore, Maryland.
Jobert Richie NansseuDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Joël Fokom DomgueDepartment of Gynecology and Obstetrics, Yaoundé University Teaching Hospital, Yaoundé, Cameroon.ORCID 0000-0002-4722-9262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive disorders of pregnancy (HDP) are a major contributor to maternal and perinatal morbidity and mortality, especially in resource-limited settings. Little is known about the magnitude of HDP in Africa. We conducted the first systematic review and meta-analysis to summarize available data on the prevalence of HDP in Africa. We did a comprehensive literature search to identify review paper published from January 1, 1996, to September 30, 2017, and searched the reference list of retrieved review paper. We used a random-effects model to estimate the overall and type-specific prevalence of HDP in Africa. We included 82 studies published between 1997 and 2017 reporting data on a pooled sample of 854 304 women during pregnancy or puerperium. Most studies were hospital-based, conducted in urban settings across 24 countries. In this population, the overall prevalence of HDP was 100.4‰ (95% CI: 81.4-121.2). The prevalence was 49.8‰ (95% CI: 32.3-70.7) for gestational hypertension, 14.7‰ (95% CI: 11.6-18.2) for chronic hypertension, 9.2‰ (95% CI: 4.2-16.0) for superimposed preeclampsia, 44.0‰ (95% CI: 36.7-52.0) for preeclampsia, 22.1‰ (95% CI: 14.8-30.8) for severe preeclampsia, 14.7‰ (95% CI: 8.1-23.2) for eclampsia and 2.2‰ (95% CI: 1.2-3.4) for HELLP syndrome. Prevalence of HDP was significantly higher in Central and Western Africa; there was a consistent tendency of increasing HDP prevalence with income at the country level. In conclusion, the burden of HDP in Africa is high, with about one in 10 pregnancies affected. The higher rate of severe forms of HDP that are associated with significant maternal and perinatal mortality is a major concern in the region.

Indexed as

AdultAfricaCost of IllnessFemaleHELLP SyndromeHumansHypertension, Pregnancy-InducedInfant, NewbornMaternal MortalityPerinatal MortalityPre-EclampsiaPregnancyPrevalenceRisk FactorsSeverity of Illness IndexSocial ClassAfricaeclampsiagestational hypertensionHELLP syndromehypertensionpreeclampsiapregnancypregnancy-induced hypertension

Identifiers

PMID30848083
PMCPMC8030504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.