ArticleZoonoses and public health2019
Evolution of rotavirus C in humans and several domestic animal species.
Article in Zoonoses and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Expanded detection of canine enteric viruses in UK dogs with diarrhoea.Microbial genomics · 2026Article
- Prevalence and genetic characterization of diarrhea viruses among cattle in Guangdong, China.BMC veterinary research · 2025Article
- Seroepidemiology of Human Non-Species A Rotavirus Infections in Valencia, Spain.Journal of medical virology · 2025Article
- Metagenomic Investigation of Pathogenic RNA Viruses Causing Diarrhea in Sika Deer Fawns.Viruses · 2025Article
- Extended analyses of rotavirus C (RVC) G-types and P-types reveal new cut-off value for the G-types and reclassification of strains.Journal of virology · 2025Article
- Diversity and Potential Cross-Species Transmission of Rotavirus A in Wild Animals in Yunnan, China.Microorganisms · 2025Article
- Control of Neonatal Diarrhea in Piglets with Reduced Antibiotic Use by Application of a Complementary Feed-A Randomized Controlled Farm Trial.Veterinary sciences · 2025Article
- Complete genome characterization by nanopore sequencing of rotaviruses A, B, and C circulating on large-scale pig farms in Russia.Virology journal · 2024Article
- Identification and Genetic Analysis of Species D Rotaviruses in Pangolin Samples.Transboundary and emerging diseases · 2024Article
- Differential transcriptome response following infection of porcine ileal enteroids with species A and C rotaviruses.Virology journal · 2023Article
- Molecular Characterization of Avian Rotaviruses F and G Detected in Brazilian Poultry Flocks.Viruses · 2023Article
- Article
- Genome Analysis of the G6P6 Genotype of Porcine Group C Rotavirus in China.Animals : an open access journal from MDPI · 2022Article
- Rotavirus C Replication in Porcine Intestinal Enteroids Reveals Roles for Cellular Cholesterol and Sialic Acids.Viruses · 2022Article
- Rotavirus F and G circulating in chickens in Southeastern Brazil.Tropical animal health and production · 2022Article
- Identification of a Ruminant Origin Group B Rotavirus Associated with Diarrhea Outbreaks in Foals.Viruses · 2021Article
- Rotavirus A, C, and H in Brazilian pigs: potential for zoonotic transmission of RVA.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021Article
- Rotavirus infection in children in Southeast Asia 2008-2018: disease burden, genotype distribution, seasonality, and vaccination.Journal of biomedical science · 2020Review
- Metagenomic sequencing generates the whole genomes of porcine rotavirus A, C, and H from the United States.PloS one · 2020Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Rotavirus C (RVC) causes enteric disease in multiple species, including humans, swine, bovines, and canines. To date, the evolutionary relationships of RVC populations circulating in different host species are poorly understood, owing to the low availability of genetic sequence data. To address this gap, we sequenced 45 RVC complete genomes from swine samples collected in the United States and Mexico. A phylogenetic analysis of each genome segment indicates that RVC populations have been evolving independently in human, swine, canine, and bovine hosts for at least the last century, with inter-species transmission events occurring deep in the phylogenetic tree, and none in the last 100 years. Bovine and canine RVC populations clustered together nine of the 11 gene segments, indicating a shared common ancestor centuries ago. The evolutionary relationships of RVC in humans and swine were more complex, due to the extensive genetic diversity and multiple RVC clades identified in pigs, which were not structured geographically. Topological differences between trees inferred for different genome segments occurred frequently, including at nodes deep in the tree, indicating that RVC's evolutionary history includes multiple reassortment events that occurred a long time ago. Overall, we find that RVC is evolving within host-defined lineages, but the evolutionary history of RVC is more complex than previously recognized due to the high genetic diversity of RVC in swine, with a common ancestor dating back centuries. Pigs may act as a reservoir host for RVC, and a source of the lineages identified in other species, including humans, but additional sequencing is needed to understand the full diversity of this understudied pathogen across multiple host species.
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