ArticleHemodialysis international. International Symposium on Home Hemodialysis2019
Brain natriuretic peptide reflects individual variation in hydration status in hemodialysis patients.
Article in Hemodialysis international. International Symposium on Home Hemodialysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Influence of dry weight reduction on anemia in patients undergoing hemodialysis.The Journal of international medical research · 2019Trial
- Association Between Brain Natriuretic Peptide and Intradialytic Hypotension in Hemodialysis Patients: A Retrospective Study.Journal of clinical medicine · 2026Article
- Association Between the Early Postoperative Changes in Serum Brain Natriuretic Peptide and Allograft Survival After Kidney Transplantation: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Brain natriuretic peptide is a biomarker of atrial fibrillation in hemodialysis patients.Renal failure · 2025Observational
- Brain natriuretic peptide and all-cause mortality in patients treated with haemodialysis.BMC nephrology · 2025Observational
- Clinical impact of very high-power-short-duration catheters on biomarkers after atrial fibrillation ablation.Journal of arrhythmia · 2025Article
- Correlation between cognitive impairment and body composition indicators in patients with chronic kidney disease after hemodialysis.American journal of translational research · 2024Article
- Associations between N-Terminal Pro-B-Type Natriuretic Peptide, Body Fluid Imbalance and Quality of Life in Patients Undergoing Hemodialysis: A Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Article
- Association between Intra- and Extra-Cellular Water Ratio Imbalance and Natriuretic Peptides in Patients Undergoing Hemodialysis.Nutrients · 2023Article
- Natriuretic peptides, extracellular volume, and subclinical cardiovascular changes in chronic kidney disease stages 1-3: a pilot study.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022Article
- B-type natriuretic peptide levels and volume status in twice-weekly hemodialysis patients.Renal failure · 2021Article
- Discontinuation of Hemodialysis After 8 Years in Favor of Toprak's Kidney Care in a Patient with End-Stage Kidney Disease.The American journal of case reports · 2021Article
- Integrating Monitoring of Volume Status and Blood Volume-Controlled Ultrafiltration into Extracorporeal Kidney Replacement Therapy.International journal of nephrology and renovascular disease · 2021Article
- Association of N-Terminal Pro-brain Natriuretic Peptide With Volume Status and Cardiac Function in Hemodialysis Patients.Frontiers in cardiovascular medicine · 2021Article
- Do Natriuretic Peptide Measurements Provide Insights into Management of End-Stage Renal Disease Patients Undergoing Dialysis?Current heart failure reports · 2020Review
- Efficacy of visceral fat estimation by dual bioelectrical impedance analysis in detecting cardiovascular risk factors in patients with type 2 diabetes.Cardiovascular diabetology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
introductionFluid management in hemodialysis patients is a controversial topic. Brain natriuretic peptide (BNP) is secreted from the heart in response to volume overload, and may be a marker of overhydration in hemodialysis patients. Our aim was to investigate the correlation between BNP and overhydration in a cohort of hemodialysis patients, and to find out whether BNP and overhydration correlate in repeated measurements within individuals with elevated BNP.
methodsThe study was prospective, observational, and had a cross-sectional part and a longitudinal follow-up. The distribution of BNP was investigated in a cohort of 64 hemodialysis patients. Blood samples and bioimpedance spectroscopy measurements were performed before midweek dialysis. Subsequently, 11 study participants with elevated BNP concentrations (>500 pg/mL) were assessed in another nine dialysis sessions each. These individuals also had their cardiac function and heart rate variability (HRV) examined.
findingsBNP was above 500 pg/mL in 38% of the participants, and correlated positively with overhydration (r DISCUSSION: BNP correlates positively to overhydration, malnutrition, and inflammation. In a subgroup of patients with elevated BNP, who are mainly elderly and frail, BNP reflects individual variation in hydration status, and hence seems to be a modifiable marker of overhydration. These data suggest that BNP is best applied for measuring changes in hydration status within an individual over time.
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